Table 2 Quantitative real-time PCR... | American Society of Hematology

Table 2

Quantitative real-time PCR validation of homozygous deletions in MCL

Sample	FAF1 (1p32.3)*	MAP2 (2q34)*	SP100(2q37)*	MOBKL2B (9p21.2)*	PRAME (22q11.22)*
GRANTA519	0.6	1.1	1.2	0.6	0†
HBL2	0.9	1	1.4	1.0	0†
JEKO1	0.5	0.5	0.1†	0.5	1.0
JVM2	1.2	0.9	1.5	1.6	0.9
MAVER1	1.0	0.9	1.2	0†	1.2
MINO	1.1	1.7	0†	1.3	0.5
NCEB1	1.2	1.2	1.0	0.3	0.5
REC1	1.1	0.6	0.5	1.8	0.9
UPN1	0†	0†	1.9	0.5	0.8
Z138	1.2	1.1	1.2	1.0	1.0
MCL validation set	3/21	ND	7/21	5/21	4‡/21

Sample	FAF1 (1p32.3)*	MAP2 (2q34)*	SP100(2q37)*	MOBKL2B (9p21.2)*	PRAME (22q11.22)*
GRANTA519	0.6	1.1	1.2	0.6	0†
HBL2	0.9	1	1.4	1.0	0†
JEKO1	0.5	0.5	0.1†	0.5	1.0
JVM2	1.2	0.9	1.5	1.6	0.9
MAVER1	1.0	0.9	1.2	0†	1.2
MINO	1.1	1.7	0†	1.3	0.5
NCEB1	1.2	1.2	1.0	0.3	0.5
REC1	1.1	0.6	0.5	1.8	0.9
UPN1	0†	0†	1.9	0.5	0.8
Z138	1.2	1.1	1.2	1.0	1.0
MCL validation set	3/21	ND	7/21	5/21	4‡/21

ND indicates not done.

In the cell lines, the number refers to qPCR result of gene dosage, whereas in the MCL primary cases, the number refers to number of cases with monoallelic loss/no. of cases analyzed.

†

Homozygous deletions.

‡

Two cases showed homozygous deletions of the PRAME gene.

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