Differential blood smear counts from myeloid-deleted mice
| Genotype . | Peripheral WBCs, % . | ||||
|---|---|---|---|---|---|
| Lymphocytes . | Neutrophils . | Bands . | Monocytes . | Eosinophils . | |
| Littemate control | 78 ± 11 | 14 ± 8 | 0 ± 0 | 7 ± 3 | 1 ± 1 |
| Mcl-1f/null plus LysM-Cre | 96 ± 2 | 0 ± 0* | 1 ± 1 | 2 ± 2 | 1 ± 1 |
| Bimf/f plus LysM-Cre | 83 ± 4 | 14 ± 5 | 0 ± 0 | 2 ± 1 | 1 ± 1 |
| Mcl-1f/nullBimf/f plus LysM-Cre | 97 ± 1 | 0 ± 0* | 0 ± 0 | 2 ± 1 | 1 ± 2 |
| Pumanull | 84 ± 5 | 9 ± 2 | 1 ± 0 | 6 ± 2 | 2 ± 1 |
| Mcl-1f/null Pumanull plus LysM-Cre | 90 ± 5 | 0 ± 1* | 0 ± 0 | 6 ± 6 | 3 ± 2 |
| Mcl-1f/null Bimf/fPumanull plus LysM-Cre | 95 ± 3 | 2 ± 1* | 0 ± 0 | 3 ± 2 | 0 ± 0 |
| Baxf/fBaknull plus LysM-Cre | 75 ± 10 | 14 ± 7 | 1 ± 2 | 10 ± 5 | 0 ± 1 |
| Mcl-1f/f Baxf/f Baknull plus LysM-Cre | 91 ± 4 | 7 ± 3 | 0 ± 1 | 1 ± 1 | 0 ± 0 |
| Genotype . | Peripheral WBCs, % . | ||||
|---|---|---|---|---|---|
| Lymphocytes . | Neutrophils . | Bands . | Monocytes . | Eosinophils . | |
| Littemate control | 78 ± 11 | 14 ± 8 | 0 ± 0 | 7 ± 3 | 1 ± 1 |
| Mcl-1f/null plus LysM-Cre | 96 ± 2 | 0 ± 0* | 1 ± 1 | 2 ± 2 | 1 ± 1 |
| Bimf/f plus LysM-Cre | 83 ± 4 | 14 ± 5 | 0 ± 0 | 2 ± 1 | 1 ± 1 |
| Mcl-1f/nullBimf/f plus LysM-Cre | 97 ± 1 | 0 ± 0* | 0 ± 0 | 2 ± 1 | 1 ± 2 |
| Pumanull | 84 ± 5 | 9 ± 2 | 1 ± 0 | 6 ± 2 | 2 ± 1 |
| Mcl-1f/null Pumanull plus LysM-Cre | 90 ± 5 | 0 ± 1* | 0 ± 0 | 6 ± 6 | 3 ± 2 |
| Mcl-1f/null Bimf/fPumanull plus LysM-Cre | 95 ± 3 | 2 ± 1* | 0 ± 0 | 3 ± 2 | 0 ± 0 |
| Baxf/fBaknull plus LysM-Cre | 75 ± 10 | 14 ± 7 | 1 ± 2 | 10 ± 5 | 0 ± 1 |
| Mcl-1f/f Baxf/f Baknull plus LysM-Cre | 91 ± 4 | 7 ± 3 | 0 ± 1 | 1 ± 1 | 0 ± 0 |
Compilation of average manual differential blood cell counts for cohorts of age-matched mice of indicated genotypes. Each data set is composed of at least 3 mice per group. Error represents SEM.
P < .01 by 2-tailed t test when compared with littermate control population.