Two-compartment population parameter and variability estimates with body surface area (BSA) as a covariate on CL
| . | Estimate . | IIV . | IOV . |
|---|---|---|---|
| CL, L/h | 31.4 (5.4) | 28.7 (25.3) | 26.0 (43.7) |
| θ | 0.84 (52.3) | ||
| V1, L | 65.8 (3.7) | 13.7 (69.0) | 9.4 (241) |
| Q, L/h | 8.49 (10.7) | 66.9 (24.2) | 73.1 (63.3) |
| V2, L | 157 (6.0) | 87.4 (32.7) | - |
| . | Estimate . | IIV . | IOV . |
|---|---|---|---|
| CL, L/h | 31.4 (5.4) | 28.7 (25.3) | 26.0 (43.7) |
| θ | 0.84 (52.3) | ||
| V1, L | 65.8 (3.7) | 13.7 (69.0) | 9.4 (241) |
| Q, L/h | 8.49 (10.7) | 66.9 (24.2) | 73.1 (63.3) |
| V2, L | 157 (6.0) | 87.4 (32.7) | - |
θ is an estimated population parameter (exponent on the normalized BSA value, BSAθ). Interindividual variability (IIV) and interoccasion variability (IOV) estimates are represented as % CV. Relative standard errors (RSE as % CV) for estimated parameters are shown in parentheses.