All adverse reactions reported by patients on study
| Adverse reaction . | Patients reporting reaction, n . | Reaction probably related to R788 . |
|---|---|---|
| Drowsiness/fatigue | 7 | No |
| Diarrhea | 6 | Yes |
| SBP increased by > 10 mm Hg | 5 | Yes |
| Nausea | 4 | Yes |
| Headache | 4 | Yes |
| Weight gain > 5 kg | 3 | Yes |
| Vomiting | 3 | Yes |
| Abdominal pain | 3 | Yes |
| Shortness of breath | 3 | No |
| Dizziness | 2 | No |
| Constipation | 2 | Yes |
| ALT > 2× ULN | 2 | Yes |
| UTI | 1 | No |
| DVT | 1 | No |
| Chest tightness | 1 | No |
| Fever | 1 | No |
| Blurry vision | 1 | No |
| Lung hemangioma | 1 | No |
| LAD | 1 | No |
| Adverse reaction . | Patients reporting reaction, n . | Reaction probably related to R788 . |
|---|---|---|
| Drowsiness/fatigue | 7 | No |
| Diarrhea | 6 | Yes |
| SBP increased by > 10 mm Hg | 5 | Yes |
| Nausea | 4 | Yes |
| Headache | 4 | Yes |
| Weight gain > 5 kg | 3 | Yes |
| Vomiting | 3 | Yes |
| Abdominal pain | 3 | Yes |
| Shortness of breath | 3 | No |
| Dizziness | 2 | No |
| Constipation | 2 | Yes |
| ALT > 2× ULN | 2 | Yes |
| UTI | 1 | No |
| DVT | 1 | No |
| Chest tightness | 1 | No |
| Fever | 1 | No |
| Blurry vision | 1 | No |
| Lung hemangioma | 1 | No |
| LAD | 1 | No |
SBP indicates systolic blood pressure; ALT, alanine aminotransferase; ULN, upper limit of normal; UTI, urinary tract infection; DVT, deep vein thrombosis; and LAD, lymphadenopathy.