Genes in the top 5 networks generated by the differentially methylated signature between CEBPAsil and CEBPAmut cases
| No. . | Molecules in network . | Focus molecules . |
|---|---|---|
| 1 | ADAMTS9, BARX1, CaMKII, CD180, CDH8, CHAT (includes EG:1103), DRD1, ELAVL3, FGF5, GNAS, GRIN2B, Gs-coupled receptor, HTR7, IGHM, IGKC, ISL1, KRT17, KRT19, LHX3, MAP6, MEOX2, MNX1, NEFL, NEFM, NEUROD1, NEUROG3, NFkB, NKX2–2, PAX1, PENK, PTPN13, RASGRF1, SATB2, TLR1, TLR8 | 32 |
| 2 | CCK, CDKN2B, CDX2, CEBPA, COL4A1, cyclin A, E2f, EID2, ESX1, FOXG1, HGF, HIST1H2BJ, histone h3, insulin, IRF8, JTV1, LRAT, Mapk, MARCKS (includes EG:4082), PGR, PITX2, POU2F3, POU3F2, PRLR, PTGFR, Rap1, Ras, RASA2, Rb, RELN, Rsk, Smad1/5/8, SMPDL3A, TFAP2C, VEGF | 24 |
| 3 | alkaline phosphatase, ALPL, APOB, ATOH1, BMP, BMP3, BMP6, BMP7, FCGR2B, FOXA2, FOXC2, GSC, IL1, LDL, LPL, LRP6, MHC class II, Mmp, MSX2, NELL1, ONECUT2, OSBPL6, P38 MAPK, PCDHGC3, PDGF BB, PLC-γ, PTHLH, SFRP1, SOX9, TGF-β, UCP2, Wnt, WNT2, WNT10B, ZAK | 24 |
| 4 | ACTN2, ADCY1, adenylate cyclase, AFAP1, α-actinin, BDNF, Cacna1, CACNA1A, CACNA1E, CACNA1I, CACNA2D1, CALML5, calmodulin, F actin, FOXL1, GAL, GALR1, GRIN3A, GRM1, Jnk, KCNN2, MARCKSL1, MBP, N-type calcium channel, NMDA receptor, OCLN, OPRK1, PDLIM3, Pkc(s), PP2A, SLC6A2, SLC6A5, SNAP25, TAC1, voltage gated calcium channel | 24 |
| 5 | ADAM12, Akt, BRCA2, cofilin, creatine kinase, Creb, CYR61, EFNA5, EPHA, EPHA2, EPHA3, EPHA5, EPHA7, EPHA/B, GABBR2, GDNF, GFRA1, GREM1, HABP4, HSPB8, HTR1B, IRS4, MAGI1, N-cor, NAE1, p70 S6k, Pdgf, PDGFC, PI3K, PIK3R1, PRKCZ, Rab5, RET, Rock, TOP2B | 23 |
| No. . | Molecules in network . | Focus molecules . |
|---|---|---|
| 1 | ADAMTS9, BARX1, CaMKII, CD180, CDH8, CHAT (includes EG:1103), DRD1, ELAVL3, FGF5, GNAS, GRIN2B, Gs-coupled receptor, HTR7, IGHM, IGKC, ISL1, KRT17, KRT19, LHX3, MAP6, MEOX2, MNX1, NEFL, NEFM, NEUROD1, NEUROG3, NFkB, NKX2–2, PAX1, PENK, PTPN13, RASGRF1, SATB2, TLR1, TLR8 | 32 |
| 2 | CCK, CDKN2B, CDX2, CEBPA, COL4A1, cyclin A, E2f, EID2, ESX1, FOXG1, HGF, HIST1H2BJ, histone h3, insulin, IRF8, JTV1, LRAT, Mapk, MARCKS (includes EG:4082), PGR, PITX2, POU2F3, POU3F2, PRLR, PTGFR, Rap1, Ras, RASA2, Rb, RELN, Rsk, Smad1/5/8, SMPDL3A, TFAP2C, VEGF | 24 |
| 3 | alkaline phosphatase, ALPL, APOB, ATOH1, BMP, BMP3, BMP6, BMP7, FCGR2B, FOXA2, FOXC2, GSC, IL1, LDL, LPL, LRP6, MHC class II, Mmp, MSX2, NELL1, ONECUT2, OSBPL6, P38 MAPK, PCDHGC3, PDGF BB, PLC-γ, PTHLH, SFRP1, SOX9, TGF-β, UCP2, Wnt, WNT2, WNT10B, ZAK | 24 |
| 4 | ACTN2, ADCY1, adenylate cyclase, AFAP1, α-actinin, BDNF, Cacna1, CACNA1A, CACNA1E, CACNA1I, CACNA2D1, CALML5, calmodulin, F actin, FOXL1, GAL, GALR1, GRIN3A, GRM1, Jnk, KCNN2, MARCKSL1, MBP, N-type calcium channel, NMDA receptor, OCLN, OPRK1, PDLIM3, Pkc(s), PP2A, SLC6A2, SLC6A5, SNAP25, TAC1, voltage gated calcium channel | 24 |
| 5 | ADAM12, Akt, BRCA2, cofilin, creatine kinase, Creb, CYR61, EFNA5, EPHA, EPHA2, EPHA3, EPHA5, EPHA7, EPHA/B, GABBR2, GDNF, GFRA1, GREM1, HABP4, HSPB8, HTR1B, IRS4, MAGI1, N-cor, NAE1, p70 S6k, Pdgf, PDGFC, PI3K, PIK3R1, PRKCZ, Rab5, RET, Rock, TOP2B | 23 |