GATA-1–repressed genes
| GATA elements . | SCL complex occupancy . |
|---|---|
| G1E cells: −GATA-1 versus +GATA-1 | |
| Kit −114 kb | ↓ |
| Kit +5 kb | ↓ |
| Kit +58 kb | − |
| Kit +73 kb | ↓ |
| Gata2 −77 kb | ↓ |
| Gata2 −2.8 kb | ↓ |
| Gata2 +9.5 kb | ↓ |
| Lyl1 | ↓ |
| Rgs18* | ↓ |
| Etv6 | ↓ |
| Sox6 | ↓ |
| Tram2 | ↓ |
| GATA elements . | SCL complex occupancy . |
|---|---|
| G1E cells: −GATA-1 versus +GATA-1 | |
| Kit −114 kb | ↓ |
| Kit +5 kb | ↓ |
| Kit +58 kb | − |
| Kit +73 kb | ↓ |
| Gata2 −77 kb | ↓ |
| Gata2 −2.8 kb | ↓ |
| Gata2 +9.5 kb | ↓ |
| Lyl1 | ↓ |
| Rgs18* | ↓ |
| Etv6 | ↓ |
| Sox6 | ↓ |
| Tram2 | ↓ |
Summary of ChIP experiments (not including ChIP-on-chip data) measuring SCL recruitment at genes activated (A) or repressed (B) by GATA-1.
↓ indicates dynamic changes in SCL occupancy following increases in GATA-1 occupancy in G1E cells; +, significant enrichment compared with controls; and −, no significant signal.
HA-tagged SCL.