Patient characteristics
| . | P1 . | P2 . | P3 . | P4 . | P5 . | P6 . | P7 . | P8 . |
|---|---|---|---|---|---|---|---|---|
| Age, y | 76 | 67 | 62 | 60 | 55 | 60 | 62 | 66 |
| Sex | Female | Female | Male | Male | Male | Male | Male | Male |
| Diagnosis | MGUS | MGUS | MGUS | MGUS | Myeloma | Myeloma | Myeloma | Myeloma |
| IgH type (M protein) | IgG | IgG | IgG | IgG | IgG | IgG | IgG | IgA |
| IgL type (M protein) | Lambda | Lambda | Kappa | Kappa | Kappa | Kappa | Kappa | Kappa |
| Marrow plasma cells, % | 4 | 8 | 7 | 5-7 | 13 | 25 | 15 | 45 |
| Cytogenetics | Negative | Negative | Hyperdiploid | ND | Negative | ND | ND | ND |
| Bone disease | No | No | No | No | Yes | Yes | No | Yes |
| Prior therapy | No | No | No | No | No | No | No | 1 cycle |
| . | P1 . | P2 . | P3 . | P4 . | P5 . | P6 . | P7 . | P8 . |
|---|---|---|---|---|---|---|---|---|
| Age, y | 76 | 67 | 62 | 60 | 55 | 60 | 62 | 66 |
| Sex | Female | Female | Male | Male | Male | Male | Male | Male |
| Diagnosis | MGUS | MGUS | MGUS | MGUS | Myeloma | Myeloma | Myeloma | Myeloma |
| IgH type (M protein) | IgG | IgG | IgG | IgG | IgG | IgG | IgG | IgA |
| IgL type (M protein) | Lambda | Lambda | Kappa | Kappa | Kappa | Kappa | Kappa | Kappa |
| Marrow plasma cells, % | 4 | 8 | 7 | 5-7 | 13 | 25 | 15 | 45 |
| Cytogenetics | Negative | Negative | Hyperdiploid | ND | Negative | ND | ND | ND |
| Bone disease | No | No | No | No | Yes | Yes | No | Yes |
| Prior therapy | No | No | No | No | No | No | No | 1 cycle |
ND indicates not determined.