Table 3

Association between PZ haplotypes and nonvascular stroke, TE, and combined data

BlockHaplotypeFrequencyT:Uχ2P
HT1      
    Stroke ATG 0.735 73.2:42.2 8.35 .004 
    TE AT 0.735 49.5:32.2 3.66 .055 
    Σ stroke and TE ATG 0.735 122:80 8.79 .003 
HT2      
    Stroke GAG 0.189 39:56 3.04 .081 
    TE GA 0.183 24.5:34.5 1.69 .193 
    Σ stroke and TE GAG 0.189 64.5:94:5 5.66 .017 
HT3      
    Stroke AAG 0.034 10.2:12.2 0.19 .667 
    TE AA 0.078 9.7:19 3.00 .08 
    Σ stroke and TE AAG 0.039 20.5:25.7 0.57 .449 
HT4      
    Stroke AAA 0.031 6:13 2.57 .10 
    TE      
    Σ stroke and TE AAA 0.029 14.0:17.0 0.29 .59 
BlockHaplotypeFrequencyT:Uχ2P
HT1      
    Stroke ATG 0.735 73.2:42.2 8.35 .004 
    TE AT 0.735 49.5:32.2 3.66 .055 
    Σ stroke and TE ATG 0.735 122:80 8.79 .003 
HT2      
    Stroke GAG 0.189 39:56 3.04 .081 
    TE GA 0.183 24.5:34.5 1.69 .193 
    Σ stroke and TE GAG 0.189 64.5:94:5 5.66 .017 
HT3      
    Stroke AAG 0.034 10.2:12.2 0.19 .667 
    TE AA 0.078 9.7:19 3.00 .08 
    Σ stroke and TE AAG 0.039 20.5:25.7 0.57 .449 
HT4      
    Stroke AAA 0.031 6:13 2.57 .10 
    TE      
    Σ stroke and TE AAA 0.029 14.0:17.0 0.29 .59 

PZ indicates protein Z; TE, thromboembolism; and T:U, the ratio of transmissions to nontransmissions of the overtransmitted allele.

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