Main patient characteristics
| . | CHOP-R . | R-HDS . | Total . | P . |
|---|---|---|---|---|
| Patients, no. | 66 | 68 | 134 | — |
| M/F, no. patients (ratio) | 40/26 (1.5) | 38/30 (1.3) | 78/56 (1.4) | .57 |
| Median age, y (range) | 51 (22-59) | 51 (25-59) | 51 (22-59) | .71 |
| Histologic grades I-II, no. (%) | 50 (76) | 48 (71) | 98 (73) | .5 |
| aaIPI 2 or more, no. (%) | 61 (92) | 59 (87) | 120 (90) | .41 |
| FLIPI 3 or more, no. (%) | 34 (51) | 44 (65) | 78 (58) | .12 |
| IIL 3 or more, no. (%) | 46 (70) | 43 (63) | 89 (66) | .47 |
| Ann Arbor stage IV, no. (%) | 56 (85) | 62 (91) | 118 (88) | .25 |
| B symptoms, no. (%) | 33 (50) | 30 (44) | 63 (47) | .49 |
| ECOG performance status 2 or more, no. (%) | 42 (66) | 38 (56) | 80 (60) | .36 |
| Bulky disease, no. (%) | 37 (56) | 38 (56) | 75 (56) | .86 |
| Spleen involvment, no. (%) | 25 (38) | 25 (37) | 50 (37) | .94 |
| Bone marrow involvment, no. (%) | 53 (80) | 60 (88) | 113 (84) | .2 |
| Extranodal involvment, no. (%) | 21 (32) | 21 (31) | 42 (31) | .9 |
| Abnormal LDH, no. (%) | 32 (59) | 33 (59) | 65 (59) | .84 |
| . | CHOP-R . | R-HDS . | Total . | P . |
|---|---|---|---|---|
| Patients, no. | 66 | 68 | 134 | — |
| M/F, no. patients (ratio) | 40/26 (1.5) | 38/30 (1.3) | 78/56 (1.4) | .57 |
| Median age, y (range) | 51 (22-59) | 51 (25-59) | 51 (22-59) | .71 |
| Histologic grades I-II, no. (%) | 50 (76) | 48 (71) | 98 (73) | .5 |
| aaIPI 2 or more, no. (%) | 61 (92) | 59 (87) | 120 (90) | .41 |
| FLIPI 3 or more, no. (%) | 34 (51) | 44 (65) | 78 (58) | .12 |
| IIL 3 or more, no. (%) | 46 (70) | 43 (63) | 89 (66) | .47 |
| Ann Arbor stage IV, no. (%) | 56 (85) | 62 (91) | 118 (88) | .25 |
| B symptoms, no. (%) | 33 (50) | 30 (44) | 63 (47) | .49 |
| ECOG performance status 2 or more, no. (%) | 42 (66) | 38 (56) | 80 (60) | .36 |
| Bulky disease, no. (%) | 37 (56) | 38 (56) | 75 (56) | .86 |
| Spleen involvment, no. (%) | 25 (38) | 25 (37) | 50 (37) | .94 |
| Bone marrow involvment, no. (%) | 53 (80) | 60 (88) | 113 (84) | .2 |
| Extranodal involvment, no. (%) | 21 (32) | 21 (31) | 42 (31) | .9 |
| Abnormal LDH, no. (%) | 32 (59) | 33 (59) | 65 (59) | .84 |
— indicates not applicable.