IC50 values of HDIs and other agents in HL-60 versus HL-60/LR cells
| Agents . | HL-60, IC50 dose . | HL-60/LR, IC50 dose . | Resistance index . |
|---|---|---|---|
| Sodium butyrate, μM | 2 | 20 | 10.0 |
| TSA, nM | 200 | 3000 | 15.0 |
| Ara-C, μM | 1.5 | 5 | 3.3 |
| Etopside, μM | 1 | 5 | 5.0 |
| 17-AAG, μM | 10 | 2 | −5.0 |
| 17-DMAG, nM | 600 | 150 | −4.0 |
| Apo-2L/TRAIL, ng/mL | 150 | > 2000 | > 13.3 |
| Agents . | HL-60, IC50 dose . | HL-60/LR, IC50 dose . | Resistance index . |
|---|---|---|---|
| Sodium butyrate, μM | 2 | 20 | 10.0 |
| TSA, nM | 200 | 3000 | 15.0 |
| Ara-C, μM | 1.5 | 5 | 3.3 |
| Etopside, μM | 1 | 5 | 5.0 |
| 17-AAG, μM | 10 | 2 | −5.0 |
| 17-DMAG, nM | 600 | 150 | −4.0 |
| Apo-2L/TRAIL, ng/mL | 150 | > 2000 | > 13.3 |