Table 1

Range of cytokine producing cells from 5 patients (ADA−/− and GT) and 7 controls (ND) in 4 independent experiments

aCD3/aCD28
TPA/ionomycin
IL-2+, cells (%)IL-4+, cells (%)IFN-γ+, cells (%)IL-2+, cells (%)IL-4+, cells (%)IFN-γ+, cells (%)
ADA−/− (n = 5) 1.18-1.85* 3.6-5.6** 0.14-1.23* 66.1-72.4 44.4-89.7 14.6-37.1* 
GT (n = 5) 7.4-24.8 10-29.2 2.8-23.2 63.5-89.4 33.1-67.4 14.3-59.2 
ND (n = 7) 9.07-16.04 4.7-15.6 9.5-15.5 31.1-82.1 21.4-58.2 16.7-58.2 
aCD3/aCD28
TPA/ionomycin
IL-2+, cells (%)IL-4+, cells (%)IFN-γ+, cells (%)IL-2+, cells (%)IL-4+, cells (%)IFN-γ+, cells (%)
ADA−/− (n = 5) 1.18-1.85* 3.6-5.6** 0.14-1.23* 66.1-72.4 44.4-89.7 14.6-37.1* 
GT (n = 5) 7.4-24.8 10-29.2 2.8-23.2 63.5-89.4 33.1-67.4 14.3-59.2 
ND (n = 7) 9.07-16.04 4.7-15.6 9.5-15.5 31.1-82.1 21.4-58.2 16.7-58.2 
**

P < .01.

*

P < .05.

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