Range of cytokine producing cells from 5 patients (ADA−/− and GT) and 7 controls (ND) in 4 independent experiments
. | aCD3/aCD28 . | TPA/ionomycin . | ||||
---|---|---|---|---|---|---|
IL-2+, cells (%) . | IL-4+, cells (%) . | IFN-γ+, cells (%) . | IL-2+, cells (%) . | IL-4+, cells (%) . | IFN-γ+, cells (%) . | |
ADA−/− (n = 5) | 1.18-1.85* | 3.6-5.6** | 0.14-1.23* | 66.1-72.4 | 44.4-89.7 | 14.6-37.1* |
GT (n = 5) | 7.4-24.8 | 10-29.2 | 2.8-23.2 | 63.5-89.4 | 33.1-67.4 | 14.3-59.2 |
ND (n = 7) | 9.07-16.04 | 4.7-15.6 | 9.5-15.5 | 31.1-82.1 | 21.4-58.2 | 16.7-58.2 |
. | aCD3/aCD28 . | TPA/ionomycin . | ||||
---|---|---|---|---|---|---|
IL-2+, cells (%) . | IL-4+, cells (%) . | IFN-γ+, cells (%) . | IL-2+, cells (%) . | IL-4+, cells (%) . | IFN-γ+, cells (%) . | |
ADA−/− (n = 5) | 1.18-1.85* | 3.6-5.6** | 0.14-1.23* | 66.1-72.4 | 44.4-89.7 | 14.6-37.1* |
GT (n = 5) | 7.4-24.8 | 10-29.2 | 2.8-23.2 | 63.5-89.4 | 33.1-67.4 | 14.3-59.2 |
ND (n = 7) | 9.07-16.04 | 4.7-15.6 | 9.5-15.5 | 31.1-82.1 | 21.4-58.2 | 16.7-58.2 |