Differences in disease complication prevalences between centers
| Complication . | Prevalence by center, % . | P . | ||||
|---|---|---|---|---|---|---|
| Gothenberg . | Stockholm . | Freiburg . | Oxford . | Brno . | ||
| Iron deficiency | 22 | 4 | 18 | 56 | 29 | < .001 |
| Lymphadenopathy: persistent | 0 | 7 | 9 | 23 | 42 | < .001 |
| Splenomegaly | 3 | 19 | 46 | 30 | 66 | < .001 |
| Bronchiectasis | 14 | 4 | 16 | 52 | 27 | < .001 |
| No complications | 43 | 46 | 24 | 12 | 5 | < .001 |
| Lymphoid interstitial pneumonitis | 0 | 0 | 0 | 10 | 0 | < .001 |
| Hepatomegaly: unexplained | 0 | 5 | 13 | 15 | 7 | .008 |
| Granuloma: unexplained | 4 | 2 | 10 | 16 | 5 | .01 |
| Immune thrombocytopenia | 3 | 4 | 12 | 13 | 0 | .01 |
| Psoriasis | 0 | 2 | 0 | 6 | 0 | .02 |
| Enteropathy: unexplained | 3 | 4 | 10 | 13 | 15 | .06 |
| Pernicious anemia | 4 | 18 | 10 | 6 | 10 | .08 |
| Autoimmune hemolytic anemia | 1 | 4 | 3 | 8 | 0 | .08 |
| Thyrotoxicosis | 0 | 0 | 0 | 2 | 0 | .26 |
| Hypothyroidism | 0 | 4 | 6 | 5 | 7 | .28 |
| Persistent arthropathy | 1 | 2 | 6 | 2 | 5 | .46 |
| Neutropenia | 0 | 2 | 0 | 1 | 2 | .66 |
| Vitiligo | 6 | 5 | 6 | 5 | 5 | 1.0 |
| Complication . | Prevalence by center, % . | P . | ||||
|---|---|---|---|---|---|---|
| Gothenberg . | Stockholm . | Freiburg . | Oxford . | Brno . | ||
| Iron deficiency | 22 | 4 | 18 | 56 | 29 | < .001 |
| Lymphadenopathy: persistent | 0 | 7 | 9 | 23 | 42 | < .001 |
| Splenomegaly | 3 | 19 | 46 | 30 | 66 | < .001 |
| Bronchiectasis | 14 | 4 | 16 | 52 | 27 | < .001 |
| No complications | 43 | 46 | 24 | 12 | 5 | < .001 |
| Lymphoid interstitial pneumonitis | 0 | 0 | 0 | 10 | 0 | < .001 |
| Hepatomegaly: unexplained | 0 | 5 | 13 | 15 | 7 | .008 |
| Granuloma: unexplained | 4 | 2 | 10 | 16 | 5 | .01 |
| Immune thrombocytopenia | 3 | 4 | 12 | 13 | 0 | .01 |
| Psoriasis | 0 | 2 | 0 | 6 | 0 | .02 |
| Enteropathy: unexplained | 3 | 4 | 10 | 13 | 15 | .06 |
| Pernicious anemia | 4 | 18 | 10 | 6 | 10 | .08 |
| Autoimmune hemolytic anemia | 1 | 4 | 3 | 8 | 0 | .08 |
| Thyrotoxicosis | 0 | 0 | 0 | 2 | 0 | .26 |
| Hypothyroidism | 0 | 4 | 6 | 5 | 7 | .28 |
| Persistent arthropathy | 1 | 2 | 6 | 2 | 5 | .46 |
| Neutropenia | 0 | 2 | 0 | 1 | 2 | .66 |
| Vitiligo | 6 | 5 | 6 | 5 | 5 | 1.0 |
The P value provides the statistical evidence against the hypothesis of equal intercenter rates for each disease complication.