Table 1 Summary of the genetic and... | American Society of Hematology

Table 1

Summary of the genetic and epigenetic abnormalities in ATLL cell lines

Cell line	Cell type	10p abnormalities	Point mutation	Treatment
Cell line	Cell type	10p abnormalities	Point mutation	5-Aza-dC, fold ± SD	TSA, fold ± SD	5-Aza-dC+TSA, fold ± SD
MOLT4	T-ALL	None	None	1.25 ± 0.46	1.65 ± 0.21	1.65 ± 0.22
Jurkat	T-ALL	None	None	11.17 ± 0.59*	10.04 ± 1.74*	3.07 ± 0.54*
MT2	HTLV-1 (+)	None	None	3.38 ± 1.17*	8.25 ± 1.76*	4.58 ± 0.90*
HUT102	HTLV-1 (+)	None	255A>C Asn78Thr	4.39 ± 0.49*	6.94 ± 0.16*	8.03 ± 1.05*
ED	ATLL	None	None	4.32 ± 1.57*	7.48 ± 0.91*	3.93 ± 0.21*
KOB	ATLL	10p del	None	3.26 ± 1.12*	2.32 ± 0.81	2.08 ± 0.54
KK1	ATLL	10p del	None	9.92 ± 0.45*	6.76 ± 0.17*	9.72 ± 0.35*
SO4	ATLL	10p del	None	1.40 ± 0.33	1.57 ± 0.18	0.59 ± 0.06
S1T	ATLL	None	None	3.66 ± 0.21*	3.95 ± 0.75*	2.32 ± 1.63
Su9T	ATLL	None	None	3.91 ± 0.45*	9.66 ± 2.38*	1.42 ± 0.21

Cell line	Cell type	10p abnormalities	Point mutation	Treatment
Cell line	Cell type	10p abnormalities	Point mutation	5-Aza-dC, fold ± SD	TSA, fold ± SD	5-Aza-dC+TSA, fold ± SD
MOLT4	T-ALL	None	None	1.25 ± 0.46	1.65 ± 0.21	1.65 ± 0.22
Jurkat	T-ALL	None	None	11.17 ± 0.59*	10.04 ± 1.74*	3.07 ± 0.54*
MT2	HTLV-1 (+)	None	None	3.38 ± 1.17*	8.25 ± 1.76*	4.58 ± 0.90*
HUT102	HTLV-1 (+)	None	255A>C Asn78Thr	4.39 ± 0.49*	6.94 ± 0.16*	8.03 ± 1.05*
ED	ATLL	None	None	4.32 ± 1.57*	7.48 ± 0.91*	3.93 ± 0.21*
KOB	ATLL	10p del	None	3.26 ± 1.12*	2.32 ± 0.81	2.08 ± 0.54
KK1	ATLL	10p del	None	9.92 ± 0.45*	6.76 ± 0.17*	9.72 ± 0.35*
SO4	ATLL	10p del	None	1.40 ± 0.33	1.57 ± 0.18	0.59 ± 0.06
S1T	ATLL	None	None	3.66 ± 0.21*	3.95 ± 0.75*	2.32 ± 1.63
Su9T	ATLL	None	None	3.91 ± 0.45*	9.66 ± 2.38*	1.42 ± 0.21

Data are means plus or minus SD.

P < .05 versus control (Dunnett test).