Table 5 Grades 3 to 4 toxic effects of... | American Society of Hematology

Table 5

Grades 3 to 4 toxic effects of thalidomide in patients with newly diagnosed MM

Regimen	No. patients	Thrombocytopenia, %	Neutropenia, %	Infection, %	Peripheral neuropathy, %	Reference
Dexamethasone
TD	235	1	3	ND	2	52 *†
TD	103	ND	ND	7	7	31 *
TD	100	ND	0	4	4	32
TD	50	ND	ND	ND	2	30
TD	100	ND	ND	ND	ND	33 *
Melphalan
MPT	129	3	16	10	8	37 *
MPT	125	14	48	13	6	38 *
MPT	113	ND	23‡	ND	20‡	39 *
Doxorubicin
ThaDD	50	0	12	22	0	44
T-VAD doxil	117	8‡	10‡	7	6‡	45 *
T-VAD doxil	39	15	15	21	5	40
Cyclophosphamide, CTD	27	ND	4	7	4	47

Regimen	No. patients	Thrombocytopenia, %	Neutropenia, %	Infection, %	Peripheral neuropathy, %	Reference
Dexamethasone
TD	235	1	3	ND	2	52 *†
TD	103	ND	ND	7	7	31 *
TD	100	ND	0	4	4	32
TD	50	ND	ND	ND	2	30
TD	100	ND	ND	ND	ND	33 *
Melphalan
MPT	129	3	16	10	8	37 *
MPT	125	14	48	13	6	38 *
MPT	113	ND	23‡	ND	20‡	39 *
Doxorubicin
ThaDD	50	0	12	22	0	44
T-VAD doxil	117	8‡	10‡	7	6‡	45 *
T-VAD doxil	39	15	15	21	5	40
Cyclophosphamide, CTD	27	ND	4	7	4	47

ND indicates not determined.

Randomized trial.

Updated information was presented at the American Society of Clinical Oncology and European Haematology Association Congress.

Grades 2 to 4.