Association of t(11;14) with hematologic parameters
| . | Overall study population, patient groups 1-4, n = 231 . | AL amyloidosis series, patient groups 1-2, n = 85 . | ||||
|---|---|---|---|---|---|---|
| t(11;14) . | No t(11;14) . | P . | t(11;14) . | No t(11;14) . | P . | |
| Intact immunoglobulin by immunofixation, no. patients (%) | 45/76 (59) | 137/155 (88) | < .001 | 7/38 (18) | 34/47 (72) | < .001 |
| Lambda light chain restriction, no. patients (%) | 43/75 (57) | 78/155 (50) | 1.0 | 26/38 (68) | 38/47 (81) | 1.0 |
| Median involved FLC concentration, mg/L | ND | ND | ND | 257 | 193 | 1.0 |
| Median plasma cell content, % | 10 | 10 | 1.0 | 10 | 10 | 1.0 |
| . | Overall study population, patient groups 1-4, n = 231 . | AL amyloidosis series, patient groups 1-2, n = 85 . | ||||
|---|---|---|---|---|---|---|
| t(11;14) . | No t(11;14) . | P . | t(11;14) . | No t(11;14) . | P . | |
| Intact immunoglobulin by immunofixation, no. patients (%) | 45/76 (59) | 137/155 (88) | < .001 | 7/38 (18) | 34/47 (72) | < .001 |
| Lambda light chain restriction, no. patients (%) | 43/75 (57) | 78/155 (50) | 1.0 | 26/38 (68) | 38/47 (81) | 1.0 |
| Median involved FLC concentration, mg/L | ND | ND | ND | 257 | 193 | 1.0 |
| Median plasma cell content, % | 10 | 10 | 1.0 | 10 | 10 | 1.0 |
Table shows the association of the CA t(11;14) with hematologic parameters [n/N(%)]. he strongest association was detected between the detection of t(11;14) and the lack of an intact immunoglobulin.
FLC indicates full light chain; ND, not determined.