Table 5

Prognostic factors in univariate analysis that predicted FFS or OS in ALK+ and ALK− ALCL

Clinical featuresALK+
ALK−
OSFFSOSFFS
Age over 60 y < .001 .025 .14 .50 
Male sex .80 .69 .43 .73 
PS more than 2 .01 .003 < .001 < .001 
Stage* .003 .04 .04 .016 
Elevated LDH .006 .02 .003 .007 
Extranodal sites more than 1 < .001 < .001 .06 .096 
Bulky disease more than 10 cm .72 .30 .33 .73 
B symptoms .18 .47 .14 .04 
Hemoglobin less than 110 × g/L .04 < .001 .50 .60 
Platelets less than 150 × 109/L .46 .71 .21 .09 
Clinical featuresALK+
ALK−
OSFFSOSFFS
Age over 60 y < .001 .025 .14 .50 
Male sex .80 .69 .43 .73 
PS more than 2 .01 .003 < .001 < .001 
Stage* .003 .04 .04 .016 
Elevated LDH .006 .02 .003 .007 
Extranodal sites more than 1 < .001 < .001 .06 .096 
Bulky disease more than 10 cm .72 .30 .33 .73 
B symptoms .18 .47 .14 .04 
Hemoglobin less than 110 × g/L .04 < .001 .50 .60 
Platelets less than 150 × 109/L .46 .71 .21 .09 
*

Stage I/II versus III versus IV.

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