Table 4

Evaluation of the sensitivity of biomarker combinations in the diagnosis of chronic GVHD

Number of positive plasma biomarkers(sBAFF, sIL-2Ra, anti-dsDNA, sCD13)*Early
Late
TotalcGVHD
cGVHDControlcGVHDControl
19 12 
13 
10 13 
Number of positive plasma biomarkers(sBAFF, sIL-2Ra, anti-dsDNA, sCD13)*Early
Late
TotalcGVHD
cGVHDControlcGVHDControl
19 12 
13 
10 13 
*

Positive values for early cGVHD as established by the ROC analysis (Table 3).

All positive values for late cGVHD values were identical to early except for sBAFF, established by an estimate (>2.0 ng/mL = positive, late) due to the fact numbers were not sufficient to perform ROC analysis.

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