Features of compounds analyzed in this study
| . | PTL . | Celastrol . | Gedunin . | HNE . | Hemin . |
|---|---|---|---|---|---|
| Terpenoid | + | + | + | − | − |
| NF-κB inhibitor | + | + | + | + | + |
| Proteasome inhibitor | nd | + | nd | + | nd |
| Oxidative stress | + | * | nd | + | + |
| . | PTL . | Celastrol . | Gedunin . | HNE . | Hemin . |
|---|---|---|---|---|---|
| Terpenoid | + | + | + | − | − |
| NF-κB inhibitor | + | + | + | + | + |
| Proteasome inhibitor | nd | + | nd | + | nd |
| Oxidative stress | + | * | nd | + | + |
nd indicates not determined.
Indicates literature reports antioxidant activity,56 Nrf2 activation in this study suggests induction of oxidative stress for AML.