Table 1

Frequencies of HSCs in the BM of young and aged B6-CD45.1 and D2-CD45.1

Cells injectedUnseparated BM
Lin
HSC frequency*No.HSC frequency*No.
D2 young 24.7 (16.3-37.3) 226.1 (136.7-373) 
B6 young 8.3 (5.4-12.7) 100.6 (75-133.6) 
D2 aged ND  248 (160-384.4) 
B6 aged 11.3 (7.2-17.8) 152.7 (77.6-300.4) 
Cells injectedUnseparated BM
Lin
HSC frequency*No.HSC frequency*No.
D2 young 24.7 (16.3-37.3) 226.1 (136.7-373) 
B6 young 8.3 (5.4-12.7) 100.6 (75-133.6) 
D2 aged ND  248 (160-384.4) 
B6 aged 11.3 (7.2-17.8) 152.7 (77.6-300.4) 
*

Frequency of HSCs per 100 000 cells injected; the 95% confidence interval is given in parentheses.

No. indicates number of experiments. For each experiment 10 to 20 hosts were injected per cell dose. Data from experiments within a group were combined to calculate the frequency.

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