mPB collections from DC subjects
| Name . | UPN 2 . | UPN 5 . | UPN 6 . | UPN 7 . | UPN 9 . |
|---|---|---|---|---|---|
| Age, y | 52 | 40 | 33 | 21 | 11 |
| Precollection CBC* | |||||
| Hgb level, g/dL | 12.8 | 13.8 | 13.2 | 12.7 | 12.1 |
| Platelet count, ×103/mm3 | 213 | 177 | 90 | 39 | 107 |
| WBC count, ×103/mm3 | 38.9 | 12.1 | 9.6 | 5.9 | 14.8 |
| ALC, ×103/mm3 | 2.8 | 1.9 | 1.3 | 1.3 | 1.8 |
| ANC, ×103/mm3 | 33.6 | 9.1 | 7.5 | 3.9 | 11.9 |
| Postcollection CBC | |||||
| Hgb level, g/dL | 11.2 | 13.1 | 11.6 | 10.7 | 10.7 |
| Platelet count, ×103/mm3 | 40 | 69 | 29 | 11 | 48 |
| WBC count, ×103/mm3 | 29.2 | 16.8 | 12.1 | 5.8 | 10.1 |
| ALC, ×103/mm3 | 0.7 | 1.1 | 0.8 | 0.7 | 1.2 |
| ANC, ×103/mm3 | 26.4 | 14.6 | 10.1 | 4.8 | 7.9 |
| mPB collection averages | |||||
| % CD34+† | 0.320 | 0.090 | 0.044 | 0.050 | 0.140 |
| No. CD34+‡ | 2.31E+08 | 9.38E+07 | 1.61E+07 | 1.66E+07 | 5.88E+07 |
| TNCs | 1.43E+11 | 1.12E+11 | 6.77E+10 | 6.43E+10 | 1.03E+11 |
| MNCs | 1.46E+09 | 9.14E+08 | 8.81E+08 | 9.67E+08 | 1.30E+09 |
| Total CD34+ cells/kg§ | 6.16E+06 | 1.93E+06 | 4.80E+05 | 5.60E+05 | 2.15E+06 |
| Total CD34+ cells | 5.30E+08 | 1.75E+08 | 3.37E+07 | 3.21E+07 | 9.72E+07 |
| Name . | UPN 2 . | UPN 5 . | UPN 6 . | UPN 7 . | UPN 9 . |
|---|---|---|---|---|---|
| Age, y | 52 | 40 | 33 | 21 | 11 |
| Precollection CBC* | |||||
| Hgb level, g/dL | 12.8 | 13.8 | 13.2 | 12.7 | 12.1 |
| Platelet count, ×103/mm3 | 213 | 177 | 90 | 39 | 107 |
| WBC count, ×103/mm3 | 38.9 | 12.1 | 9.6 | 5.9 | 14.8 |
| ALC, ×103/mm3 | 2.8 | 1.9 | 1.3 | 1.3 | 1.8 |
| ANC, ×103/mm3 | 33.6 | 9.1 | 7.5 | 3.9 | 11.9 |
| Postcollection CBC | |||||
| Hgb level, g/dL | 11.2 | 13.1 | 11.6 | 10.7 | 10.7 |
| Platelet count, ×103/mm3 | 40 | 69 | 29 | 11 | 48 |
| WBC count, ×103/mm3 | 29.2 | 16.8 | 12.1 | 5.8 | 10.1 |
| ALC, ×103/mm3 | 0.7 | 1.1 | 0.8 | 0.7 | 1.2 |
| ANC, ×103/mm3 | 26.4 | 14.6 | 10.1 | 4.8 | 7.9 |
| mPB collection averages | |||||
| % CD34+† | 0.320 | 0.090 | 0.044 | 0.050 | 0.140 |
| No. CD34+‡ | 2.31E+08 | 9.38E+07 | 1.61E+07 | 1.66E+07 | 5.88E+07 |
| TNCs | 1.43E+11 | 1.12E+11 | 6.77E+10 | 6.43E+10 | 1.03E+11 |
| MNCs | 1.46E+09 | 9.14E+08 | 8.81E+08 | 9.67E+08 | 1.30E+09 |
| Total CD34+ cells/kg§ | 6.16E+06 | 1.93E+06 | 4.80E+05 | 5.60E+05 | 2.15E+06 |
| Total CD34+ cells | 5.30E+08 | 1.75E+08 | 3.37E+07 | 3.21E+07 | 9.72E+07 |
Hgb indicates hemoglobin (g/dL); Plt, platelet count; WBC, white blood cell; ALC, absolute lymphocyte count; ANC, absolute neutrophil count; TNCs, total nucleated cells; and MNCs, mononuclear cells.
Precollection CBC values were obtained just prior to the first apheresis, and postcollection CBC values were obtained 30 minutes following the first apheresis.
Percentage CD34+ represents average values from both collections.
Represents number of cells collected from first collection.
Average number of cells collected from healthy HSC apheresis volunteers (n=11) at University of Iowa DeGowin Blood Center = 9.13×106 CD34+ cells/kg.