Clinical characteristics of DC subjects
| Subject . | UPN 2 . | UPN 5 . | UPN 6 . | UPN 7 . | UPN 9 . | Normal range . |
|---|---|---|---|---|---|---|
| Age/generation/sex | 52/II/M | 40/II/M | 33/II/M | 21/III/F | 11/III/M | N/A |
| Weight, kg | 86 | 89 | 70 | 57 | 45 | N/A |
| Clinical findings | S,L,N | S,L,N | S,L,N | N | N | N/A |
| Hemoglobin, g/dL | 12.9 | 14.4 | 13.7 | 13.4 | 12.9 | 12.7-17.0 |
| MCV, fL | 93 | 95 | 104 | 102 | 92 | 77-90 |
| Platelet count, ×103/mm3 | 264 | 175 | 105 | 49 | 138 | 150-400 |
| WBC count, ×103/mm3 | 4.6 | 3.3 | 3.4 | 3.4 | 4.7 | 3.7-10.5 |
| ANC, ×103/mm3 | 1.426 | 1.400 | 1.360 | 1.894 | 2.350 | 1.550-6.100 |
| Subject . | UPN 2 . | UPN 5 . | UPN 6 . | UPN 7 . | UPN 9 . | Normal range . |
|---|---|---|---|---|---|---|
| Age/generation/sex | 52/II/M | 40/II/M | 33/II/M | 21/III/F | 11/III/M | N/A |
| Weight, kg | 86 | 89 | 70 | 57 | 45 | N/A |
| Clinical findings | S,L,N | S,L,N | S,L,N | N | N | N/A |
| Hemoglobin, g/dL | 12.9 | 14.4 | 13.7 | 13.4 | 12.9 | 12.7-17.0 |
| MCV, fL | 93 | 95 | 104 | 102 | 92 | 77-90 |
| Platelet count, ×103/mm3 | 264 | 175 | 105 | 49 | 138 | 150-400 |
| WBC count, ×103/mm3 | 4.6 | 3.3 | 3.4 | 3.4 | 4.7 | 3.7-10.5 |
| ANC, ×103/mm3 | 1.426 | 1.400 | 1.360 | 1.894 | 2.350 | 1.550-6.100 |
MCV indicates mean corpuscular volume; WBC, white blood cell; ANC, absolute neutrophil count; S, skin dyspigmentation; L, leukoplakia; and N, nail dystrophy.