Table 7 Genotype distributions in... | American Society of Hematology

Table 7

Genotype distributions in clinically distinct subgroups of the CLL cohort

CLL subgroup	No.	Genotype			P vs CLL	P vs counterpart
CLL subgroup	No.	CC, %	GC, %	GG, %	P vs CLL	P vs counterpart
Sex
Female	105	67	31	2	.26	.14
Male	143	58	37	5	.55	.03
Binet stage
A+C	195	63	35	3	.79	.11
B	49	57	35	8	.08	.002
Affected LN areas
2 or less	188	64	34	3	.76	.01
More than 2	50	50	42	8	.019	<.001
Spleen size
Normal	191	64	34	2	.62	.014
Enlarged	51	53	37	10	.006	<.001
LDH
450 IU/L or less	192	65	32	3	.78	<.001
More than 450 IU/L	34	38	53	9	<.001	<.001
Lines of therapy
Less than 2	170	64	33	4	.88	.002
2 or more	67	46	49	5	.008	.001

CLL subgroup	No.	Genotype			P vs CLL	P vs counterpart
CLL subgroup	No.	CC, %	GC, %	GG, %	P vs CLL	P vs counterpart
Sex
Female	105	67	31	2	.26	.14
Male	143	58	37	5	.55	.03
Binet stage
A+C	195	63	35	3	.79	.11
B	49	57	35	8	.08	.002
Affected LN areas
2 or less	188	64	34	3	.76	.01
More than 2	50	50	42	8	.019	<.001
Spleen size
Normal	191	64	34	2	.62	.014
Enlarged	51	53	37	10	.006	<.001
LDH
450 IU/L or less	192	65	32	3	.78	<.001
More than 450 IU/L	34	38	53	9	<.001	<.001
Lines of therapy
Less than 2	170	64	33	4	.88	.002
2 or more	67	46	49	5	.008	.001

Because of rounding, percentages do not always add up to 100.