Probit or ordered probit regression model for multivariate analysis
| . | Variable . | Marginal effect . | P . |
|---|---|---|---|
| CD38 30% or more, n = 102 | Mutation | −0.022 | .008 |
| Male | 0.168 | .017 | |
| Age at diagnosis | 0.006 | .026 | |
| GC | 0.027 | .531 | |
| GG | 0.037 | .666 | |
| ZAP-70 20% or more, n = 59 | Mutation | −0.048 | <.001 |
| GC + GG | 0.194 | .010 | |
| Trisomy 12 | 0.230 | .010 | |
| Splenomegaly, n = 51 | Deletion 11 | 0.420 | .004 |
| GG | 0.531 | .005 | |
| Male | 0.140 | .015 | |
| Trisomy 12 | 0.224 | .022 | |
| Deletion 17 | 0.197 | .065 | |
| Richter syndrome, n = 30 | GC | 0.124 | .007 |
| GG | 0.306 | .040 | |
| Lines of treatment, n = 67 | Trisomy 12 | 0.078 | .004 |
| Deletion 11 | 0.148 | .001 | |
| Deletion 17 | 0.112 | .005 | |
| Mutation | −0.007 | .014 |
| . | Variable . | Marginal effect . | P . |
|---|---|---|---|
| CD38 30% or more, n = 102 | Mutation | −0.022 | .008 |
| Male | 0.168 | .017 | |
| Age at diagnosis | 0.006 | .026 | |
| GC | 0.027 | .531 | |
| GG | 0.037 | .666 | |
| ZAP-70 20% or more, n = 59 | Mutation | −0.048 | <.001 |
| GC + GG | 0.194 | .010 | |
| Trisomy 12 | 0.230 | .010 | |
| Splenomegaly, n = 51 | Deletion 11 | 0.420 | .004 |
| GG | 0.531 | .005 | |
| Male | 0.140 | .015 | |
| Trisomy 12 | 0.224 | .022 | |
| Deletion 17 | 0.197 | .065 | |
| Richter syndrome, n = 30 | GC | 0.124 | .007 |
| GG | 0.306 | .040 | |
| Lines of treatment, n = 67 | Trisomy 12 | 0.078 | .004 |
| Deletion 11 | 0.148 | .001 | |
| Deletion 17 | 0.112 | .005 | |
| Mutation | −0.007 | .014 |
Marginal effect measures the variation in probability generated by a unit increase in the considered variable.