Table 3 Allele frequencies in... | American Society of Hematology

Table 3

Allele frequencies in molecularly distinct subgroups of the CLL cohort

CLL subgroup	Allele frequency			P vs CLL	P vs counterpart
CLL subgroup	No.	C	G	P vs CLL	P vs counterpart
Total cohort	248	0.79	0.21		.77 (vs control)
IgV mutational status
MUT	149	0.81	0.19	.57	.12
UM	87	0.76	0.24	.59	.24
CD38
Less than 30%	143	0.80	0.20	.37	.27
30% or more	102	0.77	0.23	.76	.56
ZAP-70
Less than 20%	131	0.82	0.18	.39	.03
20% or more	59	0.75	0.25	.32	.07
CD38⁻/ZAP-70⁻	88	0.83	0.17	.29	.027
CD38⁺/ZAP-70⁺	35	0.74	0.26	.28	.07
MUT/CD38⁻/ZAP-70⁻	73	0.84	0.16	.34	.007
UM/CD38⁺/ZAP-70⁺	25	0.72	0.28	.29	.05
Normal/del 13q	161	0.79	0.21	.51	.16
del 11q/del 17p	43	0.74	0.26	.17	.18

CLL subgroup	Allele frequency			P vs CLL	P vs counterpart
CLL subgroup	No.	C	G	P vs CLL	P vs counterpart
Total cohort	248	0.79	0.21		.77 (vs control)
IgV mutational status
MUT	149	0.81	0.19	.57	.12
UM	87	0.76	0.24	.59	.24
CD38
Less than 30%	143	0.80	0.20	.37	.27
30% or more	102	0.77	0.23	.76	.56
ZAP-70
Less than 20%	131	0.82	0.18	.39	.03
20% or more	59	0.75	0.25	.32	.07
CD38⁻/ZAP-70⁻	88	0.83	0.17	.29	.027
CD38⁺/ZAP-70⁺	35	0.74	0.26	.28	.07
MUT/CD38⁻/ZAP-70⁻	73	0.84	0.16	.34	.007
UM/CD38⁺/ZAP-70⁺	25	0.72	0.28	.29	.05
Normal/del 13q	161	0.79	0.21	.51	.16
del 11q/del 17p	43	0.74	0.26	.17	.18