Hematopoietic repopulation is influenced by Jak2
| Transplant . | Mice engrafted . | Engraftment of GFP+CD45.2+cells in peripheral blood% (range) . | Erythroid(mice withGFP+Ter119+ cells) . | Granulocytic(mice withGFP+GR-1+ cells) . | Macrophage(mice withGFP+Mac-1+ cells) . |
|---|---|---|---|---|---|
| WT-cS5 | 10 (10) | 14.8 (4-40) | 9 (10) | 10 (10) | 5 (10) |
| Jak2−/−-cS5 | 6 (8) | 8.6 (1-23) | 4 (6) | 6 (6) | 2 (6) |
| Transplant . | Mice engrafted . | Engraftment of GFP+CD45.2+cells in peripheral blood% (range) . | Erythroid(mice withGFP+Ter119+ cells) . | Granulocytic(mice withGFP+GR-1+ cells) . | Macrophage(mice withGFP+Mac-1+ cells) . |
|---|---|---|---|---|---|
| WT-cS5 | 10 (10) | 14.8 (4-40) | 9 (10) | 10 (10) | 5 (10) |
| Jak2−/−-cS5 | 6 (8) | 8.6 (1-23) | 4 (6) | 6 (6) | 2 (6) |
GFP+CD45.2+ cells correspond to transplant-derived, cS5-expressing cells. Transplant-derived erythroid cells were scored in spleen and bone marrow, and GFP+ myeloid (GR-1+ and Mac-1+) cells were measured in peripheral blood and bone marrow.