Number and percentage of ALL survivors and siblings with a chronic physical health condition, with CTCAE v3 severity score
| CTCAE v3 severity score* . | ALL survivors,† n (%) . | Siblings,†n (%) . | P‡ . |
|---|---|---|---|
| Number in each group | 2599 | 3083 | |
| No condition | 1299 (50.0) | 1919 (62.2) | |
| Grade 1, mild | 535 (20.6) | 627 (20.4) | |
| Grade 2, moderate | 376 (14.5) | 358 (11.6) | <.001‖ |
| Grade 3, severe | 250 (9.6) | 144 (4.7) | |
| Grade 4, life threatening | 127 (4.9) | 35 (1.1) | |
| Grade 5, death | 12 (0.4) | NA | |
| Any grade 1 to health condition§ | 1298 (49.9) | 1164 (37.8) | <.001 |
| Any grade 3 to 4 health condition§ | 382 (14.7) | 179 (5.8) | <.001 |
| Multiple health conditions | |||
| 2 or more health conditions | 667 (25.7) | 433 (14.0) | <.001 |
| 3 or more health conditions | 381 (14.7) | 180 (5.8) | <.001 |
| CTCAE v3 severity score* . | ALL survivors,† n (%) . | Siblings,†n (%) . | P‡ . |
|---|---|---|---|
| Number in each group | 2599 | 3083 | |
| No condition | 1299 (50.0) | 1919 (62.2) | |
| Grade 1, mild | 535 (20.6) | 627 (20.4) | |
| Grade 2, moderate | 376 (14.5) | 358 (11.6) | <.001‖ |
| Grade 3, severe | 250 (9.6) | 144 (4.7) | |
| Grade 4, life threatening | 127 (4.9) | 35 (1.1) | |
| Grade 5, death | 12 (0.4) | NA | |
| Any grade 1 to health condition§ | 1298 (49.9) | 1164 (37.8) | <.001 |
| Any grade 3 to 4 health condition§ | 382 (14.7) | 179 (5.8) | <.001 |
| Multiple health conditions | |||
| 2 or more health conditions | 667 (25.7) | 433 (14.0) | <.001 |
| 3 or more health conditions | 381 (14.7) | 180 (5.8) | <.001 |
Survivors' health conditions do not include any problems prior to the cancer diagnosis or acute problems prior to 5 years after cancer diagnosis.
NA indicates not applicable.
Common Terminology Criteria for Adverse Events version 3.
Restricted to those age 18 years and older. To be eligible, siblings had to be alive at time of enrollment. Survivors may have died in the interval between 5 years after cancer diagnosis and time of study. The composite percentage of survivors with grade 3 or 4 conditions includes conditions that were reported before the time of death in the 12 survivors who died.
Adjusted for race, sex, and age at interview.
The number may not reflect the sum of grade 1 to grade 4. Grade 1 to grade 5 was calculated by taking the maximum grade per subject. A subject with grade 5 may have other lower grades.
Comparison between no condition versus any condition.