Occurrence of exclusion criteria in patients with or without bleeding
| . | All patients with bleeding, cases . | All patients without bleeding, controls . | OR (95% CI) . | AF patients with bleeding, cases . | AF patients without bleeding, controls . | OR (95% CI) . | VTE patients with bleeding, cases . | VTE patients without bleeding, controls . | OR (95% CI) . | ACS patients with bleeding, cases . | ACS patients without bleeding, controls . | OR (95% CI) . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | 993 | 993 | — | 638 | 648 | — | 141 | 147 | — | 214 | 198 | — |
| No exclusion criteria | 597 (59.6%) | 764 (76.9%) | — | 374 (58.6%) | 490 (75.6%) | — | 105 (74.5%) | 124 (84.4%) | — | 118 (55.1%) | 150 (75.8%) | — |
| 1 exclusion criterion | 205 (20.6%) | 123 (12.4%) | 2.9 (2.2-3.9) | 121 (19.0%) | 71 (15.2%) | 3.3 (2.3-4.7) | 20 (14.2%) | 17 (11.6%) | 1.8 (0.8-3.7) | 64 (29.9%) | 35 (17.7%) | 3.1 (1.7-5.4) |
| 2 exclusion criteria | 174 (17.5%) | 102 (10.3%) | 3.8 (2.7-5.2) | 128 (20.0%) | 83 (12.8%) | 4.5 (3.0-6.7) | 15 (10.6%) | 6 (4.1%) | 4.2 (1.5-12.3) | 31(14.5%) | 13 (6.6%) | 3.9 (1.8-8.2) |
| More than 2 exclusion criteria | 17 (1.7%) | 4 (0.4%) | 14.9 (4.7-46) | 15 (2.4%) | 4 (0.6%) | 20.6 (6.2-68.6) | 1 (0.7%) | 0 (0%) | — | 1 (0.5%) | 0 (0%) | — |
| . | All patients with bleeding, cases . | All patients without bleeding, controls . | OR (95% CI) . | AF patients with bleeding, cases . | AF patients without bleeding, controls . | OR (95% CI) . | VTE patients with bleeding, cases . | VTE patients without bleeding, controls . | OR (95% CI) . | ACS patients with bleeding, cases . | ACS patients without bleeding, controls . | OR (95% CI) . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | 993 | 993 | — | 638 | 648 | — | 141 | 147 | — | 214 | 198 | — |
| No exclusion criteria | 597 (59.6%) | 764 (76.9%) | — | 374 (58.6%) | 490 (75.6%) | — | 105 (74.5%) | 124 (84.4%) | — | 118 (55.1%) | 150 (75.8%) | — |
| 1 exclusion criterion | 205 (20.6%) | 123 (12.4%) | 2.9 (2.2-3.9) | 121 (19.0%) | 71 (15.2%) | 3.3 (2.3-4.7) | 20 (14.2%) | 17 (11.6%) | 1.8 (0.8-3.7) | 64 (29.9%) | 35 (17.7%) | 3.1 (1.7-5.4) |
| 2 exclusion criteria | 174 (17.5%) | 102 (10.3%) | 3.8 (2.7-5.2) | 128 (20.0%) | 83 (12.8%) | 4.5 (3.0-6.7) | 15 (10.6%) | 6 (4.1%) | 4.2 (1.5-12.3) | 31(14.5%) | 13 (6.6%) | 3.9 (1.8-8.2) |
| More than 2 exclusion criteria | 17 (1.7%) | 4 (0.4%) | 14.9 (4.7-46) | 15 (2.4%) | 4 (0.6%) | 20.6 (6.2-68.6) | 1 (0.7%) | 0 (0%) | — | 1 (0.5%) | 0 (0%) | — |
All odds ratios are adjusted for age and sex to take the effect of frequency matching on these factors into account.
— indicates not applicable.