Univariate analysis: survival estimates according to histopathologic and phenotypic* characteristics of AITL patients
| Pathological finding . | No. . | % . | 7-y OS, % . | P . | 7-y EFS, % . | P . |
|---|---|---|---|---|---|---|
| Classic | 116 | 74 | 24 | .444 | 19 | .350 |
| Rich in epithelioid cells | 19 | 13 | — | — | — | — |
| Rich in clear cells | 14 | 9 | — | — | — | — |
| With HGC | 04 | 03 | — | — | — | — |
| Rich in large cells | 41 | 26 | 41 | — | 31 | — |
| CD10 | 52 | .634 | .870 | |||
| Score 0 | 09 | 17 | 27 | — | 14 | — |
| Score 1 | 06 | 12 | 67 | — | 33 | — |
| Score 2 | 25 | 48 | 24 | — | 29 | — |
| Score 3 | 12 | 23 | 17 | — | 8 | — |
| CXCL13 | 45 | .865 | .724 | |||
| Score 0 | 0 | 0 | — | — | — | — |
| Score 1 | 12 | 27 | 33 | — | 17 | — |
| Score 2 | 24 | 53 | 23 | — | 20 | — |
| Score 3 | 09 | 20 | 33 | — | 0 | — |
| EBV (ISH) | 103 | .557 | .386 | |||
| Negative | 25 | 24 | 15 | — | 9 | — |
| Positive | 78 | 76 | 30 | — | 21 | — |
| Pathological finding . | No. . | % . | 7-y OS, % . | P . | 7-y EFS, % . | P . |
|---|---|---|---|---|---|---|
| Classic | 116 | 74 | 24 | .444 | 19 | .350 |
| Rich in epithelioid cells | 19 | 13 | — | — | — | — |
| Rich in clear cells | 14 | 9 | — | — | — | — |
| With HGC | 04 | 03 | — | — | — | — |
| Rich in large cells | 41 | 26 | 41 | — | 31 | — |
| CD10 | 52 | .634 | .870 | |||
| Score 0 | 09 | 17 | 27 | — | 14 | — |
| Score 1 | 06 | 12 | 67 | — | 33 | — |
| Score 2 | 25 | 48 | 24 | — | 29 | — |
| Score 3 | 12 | 23 | 17 | — | 8 | — |
| CXCL13 | 45 | .865 | .724 | |||
| Score 0 | 0 | 0 | — | — | — | — |
| Score 1 | 12 | 27 | 33 | — | 17 | — |
| Score 2 | 24 | 53 | 23 | — | 20 | — |
| Score 3 | 09 | 20 | 33 | — | 0 | — |
| EBV (ISH) | 103 | .557 | .386 | |||
| Negative | 25 | 24 | 15 | — | 9 | — |
| Positive | 78 | 76 | 30 | — | 21 | — |
HGC indicates hyperplastic germinal centers; OS, overall survival; EFS, event-free survival; and ISH, in situ hybridization.
CD3, CD4, CD2, CD5, and CD7 were positive in tumor cells in 100% (157/157), 95% (52/55), 91% (41/45), 85% (46/54), and 50% (21/42), respectively.