Nominally significant associations (P < .05) between SNP genotypes and pulmonary hypertension for the adjusted analysis, including individuals with abnormal echocardiograms not consistent with pulmonary hypertension (data set 1)
Gene . | SNP . | Likelihood ratio P . | False discovery adjusted P . |
---|---|---|---|
ACVRLI | rs3847859 | .014 | .43 |
ACVRLI | rs706814 | .020 | .43 |
ADCY6 | rs9804777 | .017 | .43 |
ADRB1 | rs1801253 | .006 | .43 |
BMP6 | rs267192 | .014 | .43 |
BMP6 | rs267196 | .013 | .43 |
BMP6 | rs267201 | .019 | .43 |
BMPR2 | rs17199249 | .018 | .43 |
BMPR2 | rs35711585 | .025 | .44 |
CR1 | rs6663530 | .024 | .44 |
FY | rs3027045 | .035 | .47 |
KL | rs1888057 | .031 | .45 |
LCAT | rs5923 | .033 | .46 |
LCAT | hcv2846928 | .014 | .43 |
LTA4H | rs10492226 | < .001 | .43 |
LTA4H | rs1978331 | .022 | .44 |
SELP | rs2235302 | .014 | .43 |
SELP | rs6131 | .019 | .43 |
SERPINCI | rs2227617 | .001 | .33 |
SLC12A6 | rs426634 | .028 | .45 |
TGFBR3 | rs10874940 | .002 | .33 |
TGFBR3 | rs17443164 | .045 | .54 |
TGFBR3 | rs7526590 | .043 | .54 |
Gene . | SNP . | Likelihood ratio P . | False discovery adjusted P . |
---|---|---|---|
ACVRLI | rs3847859 | .014 | .43 |
ACVRLI | rs706814 | .020 | .43 |
ADCY6 | rs9804777 | .017 | .43 |
ADRB1 | rs1801253 | .006 | .43 |
BMP6 | rs267192 | .014 | .43 |
BMP6 | rs267196 | .013 | .43 |
BMP6 | rs267201 | .019 | .43 |
BMPR2 | rs17199249 | .018 | .43 |
BMPR2 | rs35711585 | .025 | .44 |
CR1 | rs6663530 | .024 | .44 |
FY | rs3027045 | .035 | .47 |
KL | rs1888057 | .031 | .45 |
LCAT | rs5923 | .033 | .46 |
LCAT | hcv2846928 | .014 | .43 |
LTA4H | rs10492226 | < .001 | .43 |
LTA4H | rs1978331 | .022 | .44 |
SELP | rs2235302 | .014 | .43 |
SELP | rs6131 | .019 | .43 |
SERPINCI | rs2227617 | .001 | .33 |
SLC12A6 | rs426634 | .028 | .45 |
TGFBR3 | rs10874940 | .002 | .33 |
TGFBR3 | rs17443164 | .045 | .54 |
TGFBR3 | rs7526590 | .043 | .54 |