Nominally significant associations (P < .05) between SNP genotypes and pulmonary hypertension for the unadjusted analysis, including individuals with abnormal echocardiograms not consistent with pulmonary hypertension (data set 1)
| Gene . | SNP . | Fisher exact P . | False discovery adjusted P . |
|---|---|---|---|
| ACE | rs4317 | .020 | .345 |
| ACVRL1 | rs3759178 | .016 | .345 |
| ACVRL1 | rs3847859 | .003 | .345 |
| ACVRL1 | rs706814 | .009 | .345 |
| ADCY6 | rs3730070 | .046 | .577 |
| ADRB1 | rs1801253 | .008 | .345 |
| BMP6 | rs267192 | .006 | .345 |
| BMP6 | rs267196 | .004 | .345 |
| BMP6 | rs267201 | .015 | .345 |
| BMPR2 | rs17199249 | .011 | .345 |
| BMPR2 | rs35711585 | .017 | .345 |
| CD36 | rs1527479 | .034 | .51 |
| CR1 | rs6663530 | .02 | .345 |
| F13A1 | rs4960166 | .007 | .345 |
| FY | rs3027045 | .014 | .345 |
| KL | rs1888057 | .043 | .577 |
| LCAT | rs5923 | .047 | .577 |
| LCAT | hcv2846928 | .022 | .359 |
| LCAT | rs7200210 | .024 | .382 |
| LOC255411 | rs3729972 | .003 | .345 |
| LTA4H | rs10492226 | .018 | .345 |
| NOS3 | rs1800780 | .047 | .577 |
| SELP | rs2235302 | < .001 | .161 |
| SERPINC1 | rs2227617 | .017 | .345 |
| TGFBR3 | rs10874940 | .012 | .345 |
| TGFBR3 | rs284176 | .039 | .564 |
| TGFBR3 | rs7526590 | .011 | .345 |
| Gene . | SNP . | Fisher exact P . | False discovery adjusted P . |
|---|---|---|---|
| ACE | rs4317 | .020 | .345 |
| ACVRL1 | rs3759178 | .016 | .345 |
| ACVRL1 | rs3847859 | .003 | .345 |
| ACVRL1 | rs706814 | .009 | .345 |
| ADCY6 | rs3730070 | .046 | .577 |
| ADRB1 | rs1801253 | .008 | .345 |
| BMP6 | rs267192 | .006 | .345 |
| BMP6 | rs267196 | .004 | .345 |
| BMP6 | rs267201 | .015 | .345 |
| BMPR2 | rs17199249 | .011 | .345 |
| BMPR2 | rs35711585 | .017 | .345 |
| CD36 | rs1527479 | .034 | .51 |
| CR1 | rs6663530 | .02 | .345 |
| F13A1 | rs4960166 | .007 | .345 |
| FY | rs3027045 | .014 | .345 |
| KL | rs1888057 | .043 | .577 |
| LCAT | rs5923 | .047 | .577 |
| LCAT | hcv2846928 | .022 | .359 |
| LCAT | rs7200210 | .024 | .382 |
| LOC255411 | rs3729972 | .003 | .345 |
| LTA4H | rs10492226 | .018 | .345 |
| NOS3 | rs1800780 | .047 | .577 |
| SELP | rs2235302 | < .001 | .161 |
| SERPINC1 | rs2227617 | .017 | .345 |
| TGFBR3 | rs10874940 | .012 | .345 |
| TGFBR3 | rs284176 | .039 | .564 |
| TGFBR3 | rs7526590 | .011 | .345 |