Acid α-glucosidase activity in bone marrow and spleen of mice that received a transplant of LV-SF-GAA
| Group . | Leukocytes . | Bone marrow . | Spleen . |
|---|---|---|---|
| WT (8 mo) | 3.3 ± 2.3 (n = 6) | 3.2 ± 2.6 (n = 6) | 5.2 ± 3.6 (n = 12) |
| LV-SF-GFP (8 mo) | 4.7 ± 1.3 (n = 6) | 0.5 ± 0.5 (n = 6) | 0.6 ± 0.6 (n = 15) |
| LV-SF-GAA (8 mo) | 42 ± 7 (n = 6) | 107 ± 43 (n = 5) | 249 ± 280 (n = 5) |
| LV-SF-GAA (18 mo) | 157 ± 97 (n = 4) | 132 ± 69 (n = 4) | 162 ± 111 (n = 4) |
| Group . | Leukocytes . | Bone marrow . | Spleen . |
|---|---|---|---|
| WT (8 mo) | 3.3 ± 2.3 (n = 6) | 3.2 ± 2.6 (n = 6) | 5.2 ± 3.6 (n = 12) |
| LV-SF-GFP (8 mo) | 4.7 ± 1.3 (n = 6) | 0.5 ± 0.5 (n = 6) | 0.6 ± 0.6 (n = 15) |
| LV-SF-GAA (8 mo) | 42 ± 7 (n = 6) | 107 ± 43 (n = 5) | 249 ± 280 (n = 5) |
| LV-SF-GAA (18 mo) | 157 ± 97 (n = 4) | 132 ± 69 (n = 4) | 162 ± 111 (n = 4) |
Activity displayed as α-glucosidase activity (nmol/h/mg of protein) ± SD. Values of LV-SF-GFP are background glycosidase levels.