Side effects
| Toxicities . | No. of patients (%) . | |
|---|---|---|
| Grade 1-2 . | Grade 3-4 . | |
| Extramedullary toxicities* | ||
| Fatigue | 6 (6) | — |
| Bone aches | 4 (4) | 5 (5) |
| Liver dysfunction | 10 (11) | 4 (4) |
| Skin rashes | 1 (1) | — |
| Nausea, vomiting | 17 (17) | — |
| Diarrhea | 2 (2) | — |
| Other | 9 (9) | — |
| Myelosuppression-related toxicities† | ||
| Fever of unknown origin | — | 23 (4) |
| Documented bacterial infections | ||
| Sepsis alone | — | 7 (1) |
| Minor infections | — | 24 (4) |
| Pneumonias with or without other infections | — | 20 (3.5) |
| Fungal infections | ||
| Confirmed | — | 5 (0.8) |
| Suspected | — | 1 (0.2) |
| With other infections | — | 1 (0.2) |
| Bleeding | 46 (7) | 7 (1) |
| Hospitalization | — | 110 (18) |
| Toxicities . | No. of patients (%) . | |
|---|---|---|
| Grade 1-2 . | Grade 3-4 . | |
| Extramedullary toxicities* | ||
| Fatigue | 6 (6) | — |
| Bone aches | 4 (4) | 5 (5) |
| Liver dysfunction | 10 (11) | 4 (4) |
| Skin rashes | 1 (1) | — |
| Nausea, vomiting | 17 (17) | — |
| Diarrhea | 2 (2) | — |
| Other | 9 (9) | — |
| Myelosuppression-related toxicities† | ||
| Fever of unknown origin | — | 23 (4) |
| Documented bacterial infections | ||
| Sepsis alone | — | 7 (1) |
| Minor infections | — | 24 (4) |
| Pneumonias with or without other infections | — | 20 (3.5) |
| Fungal infections | ||
| Confirmed | — | 5 (0.8) |
| Suspected | — | 1 (0.2) |
| With other infections | — | 1 (0.2) |
| Bleeding | 46 (7) | 7 (1) |
| Hospitalization | — | 110 (18) |