Cluster 3 selected up-regulated genes
| Gene symbol . | Gene name . | Fold change . | P . |
|---|---|---|---|
| FOSL1 | FOS-like antigen 1 | 3.80 | < .001 |
| SERPINB13 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13 | 3.66 | < .001 |
| MMP12 | Matrix metalloproteinase 12 (macrophage elastase) | 3.41 | .004 |
| SERPINB4 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4 | 3.33 | < .001 |
| EVA1 | Epithelial V–like antigen 1 | 3.12 | < .001 |
| SELE | Selectin E (endothelial adhesion molecule 1) | 3.08 | < .001 |
| IL13RA2 | Interleukin-13 receptor α2 | 3.05 | .006 |
| TP73L | Tumor protein p73–like | 2.94 | < .001 |
| FGFBP1 | Fibroblast growth factor–binding protein 1 | 2.86 | < .001 |
| KRT17 | Keratin 17 | 2.71 | < .001 |
| IL1RN | Interleukin-1 receptor antagonist | 2.58 | < .001 |
| CD24 | CD24 antigen (small-cell lung carcinoma cluster 4 antigen) | 2.57 | < .001 |
| KRT16 | Keratin 16 (focal nonepidermolytic palmoplantar keratoderma) | 2.54 | < .001 |
| TNFAIP6 | Tumor necrosis factor α-induced protein 6 | 2.51 | .006 |
| ID1 | Inhibitor of DNA binding 1, dominant-negative helix-loop-helix protein | 2.38 | < .001 |
| SERPINB3 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 | 2.36 | < .001 |
| DUSP1 | Dual specificity phosphatase 1 | 2.24 | .001 |
| CCL2 | Chemokine (C-C motif) ligand 2 | 2.22 | .002 |
| ITGA6 | Integrin α6 | 2.14 | < .001 |
| CEACAM1 | Carcinoembryonic antigen-related cell adhesion molecule 1 | 2.07 | .002 |
| SOCS3 | Suppressor of cytokine signaling 3 | 2.00 | .001 |
| LTB4R | Leukotriene B4 receptor | 1.95 | < .001 |
| DUSP3 | Dual specificity phosphatase 3 (vaccinia virus phosphatase VH1–related) | 1.91 | < .001 |
| ITGB4 | Integrin β4 | 1.89 | < .001 |
| KRT6A, B, C, E | Keratin 6A, keratin 6B, keratin 6C, keratin 6E | 1.89 | < .001 |
| JAG1 | Jagged 1 (Alagille syndrome) | 1.88 | < .001 |
| VEGF | Vascular endothelial growth factor | 1.88 | < .001 |
| IVL | Involucrin | 1.87 | .002 |
| MCL1 | Myeloid cell leukemia sequence 1 (BCL2-related) | 1.82 | .008 |
| TGFA | Transforming growth factor α | 1.80 | .004 |
| SERPINB1 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 | 1.79 | .001 |
| S100A2 | S100 calcium-binding protein A2 | 1.79 | < .001 |
| YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 1.77 | < .001 |
| FGFR2 | Fibroblast growth factor receptor 2 | 1.72 | < .001 |
| TNFRSF21 | Tumor necrosis factor receptor superfamily, member 21 | 1.69 | < .001 |
| RAB6A | RAB6A, member RAS oncogene family | 1.69 | .003 |
| JUNB | jun B proto-oncogene | 1.68 | < .001 |
| WNT5A | Wingless-type MMTV integration site family, member 5A | 1.65 | .006 |
| Gene symbol . | Gene name . | Fold change . | P . |
|---|---|---|---|
| FOSL1 | FOS-like antigen 1 | 3.80 | < .001 |
| SERPINB13 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13 | 3.66 | < .001 |
| MMP12 | Matrix metalloproteinase 12 (macrophage elastase) | 3.41 | .004 |
| SERPINB4 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4 | 3.33 | < .001 |
| EVA1 | Epithelial V–like antigen 1 | 3.12 | < .001 |
| SELE | Selectin E (endothelial adhesion molecule 1) | 3.08 | < .001 |
| IL13RA2 | Interleukin-13 receptor α2 | 3.05 | .006 |
| TP73L | Tumor protein p73–like | 2.94 | < .001 |
| FGFBP1 | Fibroblast growth factor–binding protein 1 | 2.86 | < .001 |
| KRT17 | Keratin 17 | 2.71 | < .001 |
| IL1RN | Interleukin-1 receptor antagonist | 2.58 | < .001 |
| CD24 | CD24 antigen (small-cell lung carcinoma cluster 4 antigen) | 2.57 | < .001 |
| KRT16 | Keratin 16 (focal nonepidermolytic palmoplantar keratoderma) | 2.54 | < .001 |
| TNFAIP6 | Tumor necrosis factor α-induced protein 6 | 2.51 | .006 |
| ID1 | Inhibitor of DNA binding 1, dominant-negative helix-loop-helix protein | 2.38 | < .001 |
| SERPINB3 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 | 2.36 | < .001 |
| DUSP1 | Dual specificity phosphatase 1 | 2.24 | .001 |
| CCL2 | Chemokine (C-C motif) ligand 2 | 2.22 | .002 |
| ITGA6 | Integrin α6 | 2.14 | < .001 |
| CEACAM1 | Carcinoembryonic antigen-related cell adhesion molecule 1 | 2.07 | .002 |
| SOCS3 | Suppressor of cytokine signaling 3 | 2.00 | .001 |
| LTB4R | Leukotriene B4 receptor | 1.95 | < .001 |
| DUSP3 | Dual specificity phosphatase 3 (vaccinia virus phosphatase VH1–related) | 1.91 | < .001 |
| ITGB4 | Integrin β4 | 1.89 | < .001 |
| KRT6A, B, C, E | Keratin 6A, keratin 6B, keratin 6C, keratin 6E | 1.89 | < .001 |
| JAG1 | Jagged 1 (Alagille syndrome) | 1.88 | < .001 |
| VEGF | Vascular endothelial growth factor | 1.88 | < .001 |
| IVL | Involucrin | 1.87 | .002 |
| MCL1 | Myeloid cell leukemia sequence 1 (BCL2-related) | 1.82 | .008 |
| TGFA | Transforming growth factor α | 1.80 | .004 |
| SERPINB1 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 | 1.79 | .001 |
| S100A2 | S100 calcium-binding protein A2 | 1.79 | < .001 |
| YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 1.77 | < .001 |
| FGFR2 | Fibroblast growth factor receptor 2 | 1.72 | < .001 |
| TNFRSF21 | Tumor necrosis factor receptor superfamily, member 21 | 1.69 | < .001 |
| RAB6A | RAB6A, member RAS oncogene family | 1.69 | .003 |
| JUNB | jun B proto-oncogene | 1.68 | < .001 |
| WNT5A | Wingless-type MMTV integration site family, member 5A | 1.65 | .006 |