Final multivariable Cox proportional hazard model for the outcome time to subsequent relapse or death
| Parameter . | No. of patients . | Hazard ratio . | 95% CI . | P . |
|---|---|---|---|---|
| Immunophenotype | < .001 | |||
| BCP | 49 | 1 | — | — |
| T lineage | 12 | 5.3 | 2.1-13.1 | — |
| Submicroscopic BM involvement at relapse diagnosis | .04 | |||
| Less than 10−4 | 16 | 1 | — | — |
| At least 10−4 | 45 | 2.7 | 1.1-6.9 | — |
| Age at relapse diagnosis | .015 | |||
| 10 y or older | 28 | 1 | — | — |
| 5 to 9 y | 23 | 0.9 | 0.4-2.0 | — |
| Younger than 5 y | 10 | 3.9 | 1.5-10.3 | — |
| Site of relapse | .001 | |||
| CNS | 38 | 1 | — | — |
| Testis | 20 | 0.24 | 0.09-0.62 | — |
| Other | 3 | 0.43 | 0.09-2.04 | — |
| Parameter . | No. of patients . | Hazard ratio . | 95% CI . | P . |
|---|---|---|---|---|
| Immunophenotype | < .001 | |||
| BCP | 49 | 1 | — | — |
| T lineage | 12 | 5.3 | 2.1-13.1 | — |
| Submicroscopic BM involvement at relapse diagnosis | .04 | |||
| Less than 10−4 | 16 | 1 | — | — |
| At least 10−4 | 45 | 2.7 | 1.1-6.9 | — |
| Age at relapse diagnosis | .015 | |||
| 10 y or older | 28 | 1 | — | — |
| 5 to 9 y | 23 | 0.9 | 0.4-2.0 | — |
| Younger than 5 y | 10 | 3.9 | 1.5-10.3 | — |
| Site of relapse | .001 | |||
| CNS | 38 | 1 | — | — |
| Testis | 20 | 0.24 | 0.09-0.62 | — |
| Other | 3 | 0.43 | 0.09-2.04 | — |
CI indicates confidence interval; BCP, B-cell precursor; BM, bone marrow; CNS, central nervous system; and —, not applicable.