Frequencies of clinical parameters in subgroups defined by submicroscopic BM involvement (cutoff: 10−4)
| Clinical parameters . | Submicroscopic BM involvement . | |||
|---|---|---|---|---|
| Total, no. (%) . | Less than 10−4, no. (%) . | At least 10−4, no. (%) . | P . | |
| Total | 64 (100) | 18 (100) | 46 (100) | — |
| Sex | .73 | |||
| Male | 52 (81) | 14 (78) | 38 (83) | — |
| Female | 12 (19) | 4 (22) | 8 (17) | — |
| Age | .68 | |||
| Less than 5 y | 10 (16) | 3 (17) | 7 (15) | — |
| 5 to 9 y | 24 (38) | 8 (44) | 16 (35) | — |
| 10 y or more | 30 (47) | 7 (39) | 23 (50) | — |
| Time point | .91 | |||
| Less than 18 mo | 24 (38) | 6 (33) | 18 (39) | — |
| 18 to less than 30 mo | 20 (31) | 6 (33) | 14 (30) | — |
| At least 30 mo | 20 (31) | 6 (33) | 14 (30) | — |
| Site | .18 | |||
| CNS* | 39 (61) | 8 (44) | 31 (67) | — |
| Testis | 21 (33) | 9 (50) | 12 (26) | — |
| Other | 4 (6) | 1 (6) | 3 (7) | — |
| Immunophenotype | .999 | |||
| BCP | 49 (80) | 13 (81) | 36 (80) | — |
| T lineage | 12 (20) | 3 (19) | 9 (20) | — |
| No data | 3 | 2 | 1 | — |
| Clinical parameters . | Submicroscopic BM involvement . | |||
|---|---|---|---|---|
| Total, no. (%) . | Less than 10−4, no. (%) . | At least 10−4, no. (%) . | P . | |
| Total | 64 (100) | 18 (100) | 46 (100) | — |
| Sex | .73 | |||
| Male | 52 (81) | 14 (78) | 38 (83) | — |
| Female | 12 (19) | 4 (22) | 8 (17) | — |
| Age | .68 | |||
| Less than 5 y | 10 (16) | 3 (17) | 7 (15) | — |
| 5 to 9 y | 24 (38) | 8 (44) | 16 (35) | — |
| 10 y or more | 30 (47) | 7 (39) | 23 (50) | — |
| Time point | .91 | |||
| Less than 18 mo | 24 (38) | 6 (33) | 18 (39) | — |
| 18 to less than 30 mo | 20 (31) | 6 (33) | 14 (30) | — |
| At least 30 mo | 20 (31) | 6 (33) | 14 (30) | — |
| Site | .18 | |||
| CNS* | 39 (61) | 8 (44) | 31 (67) | — |
| Testis | 21 (33) | 9 (50) | 12 (26) | — |
| Other | 4 (6) | 1 (6) | 3 (7) | — |
| Immunophenotype | .999 | |||
| BCP | 49 (80) | 13 (81) | 36 (80) | — |
| T lineage | 12 (20) | 3 (19) | 9 (20) | — |
| No data | 3 | 2 | 1 | — |
BM indicates bone marrow; CNS, central nervous system; BCP, B-cell precursor; and —, not applicable.
One patient with both CNS and testicular relapse.