Material for identification and confirmation of clonal relation of clone-specific markers used for submicroscopic BM involvement quantification
| Material for marker screening . | Non-IEM sample . | |
|---|---|---|
| Initial diagnosis, n = 34 . | 2nd relapse, n = 3 . | |
| Method of stabilizing clonal markers | ||
| PCR in DNA extracted from cytospins or tissue slides | 7 | 0 |
| Positive quantitative result in first relapse BM | 27 | 3 |
| Material for marker screening . | Non-IEM sample . | |
|---|---|---|
| Initial diagnosis, n = 34 . | 2nd relapse, n = 3 . | |
| Method of stabilizing clonal markers | ||
| PCR in DNA extracted from cytospins or tissue slides | 7 | 0 |
| Positive quantitative result in first relapse BM | 27 | 3 |
For the IEM samples CSF (n = 14), testis (n = 11), and other (n = 2), there was no method of stabilization necessary.