Hamster heart graft survival in C57BL/6 nude mice receiving various treatments
Group . | Recipients . | Additional treatment . | n . | Graft survival, mean d ± SD . |
---|---|---|---|---|
A | C57BL/6 nude | No | 20 | 5.1 ± 0.5 |
B | C57BL/6 nude | Splenectomy at days −90, −14, 0, 2, and 3 | 24 | No rejection* |
C | C57BL/6 nude splenectomized | Day-0 transfer of splenocytes from naive syngeneic mice | 6 | No rejection* |
D | C57BL/6 nude splenectomized | Day-0 transfer of splenocytes from xenograft-rejecting syngeneic mice | 7 | No rejection* |
E | C57BL/6 nude splenectomized | Transfer of serum from xenograft-rejecting syngeneic mice | 5 | Hyperacute rejection† |
F | C57BL/6 nude | 2 Gy TBI at day −2 | 6 | No rejection* |
G | C57BL/6 nude | 2 Gy TBI at day −14 | 4 | No rejection* |
H | C57BL/6 nude | 2 Gy TBI at day −28 | 4 | 6 ± 1.3 |
Group . | Recipients . | Additional treatment . | n . | Graft survival, mean d ± SD . |
---|---|---|---|---|
A | C57BL/6 nude | No | 20 | 5.1 ± 0.5 |
B | C57BL/6 nude | Splenectomy at days −90, −14, 0, 2, and 3 | 24 | No rejection* |
C | C57BL/6 nude splenectomized | Day-0 transfer of splenocytes from naive syngeneic mice | 6 | No rejection* |
D | C57BL/6 nude splenectomized | Day-0 transfer of splenocytes from xenograft-rejecting syngeneic mice | 7 | No rejection* |
E | C57BL/6 nude splenectomized | Transfer of serum from xenograft-rejecting syngeneic mice | 5 | Hyperacute rejection† |
F | C57BL/6 nude | 2 Gy TBI at day −2 | 6 | No rejection* |
G | C57BL/6 nude | 2 Gy TBI at day −14 | 4 | No rejection* |
H | C57BL/6 nude | 2 Gy TBI at day −28 | 4 | 6 ± 1.3 |