Comparison of kinetic values
| ADAMTS13 . | Ratio . | |||
|---|---|---|---|---|
| Km . | kcat . | |||
| VWF . | FRETS-VWF73 . | VWF . | FRETS-VWF73 . | |
| C57/FVB | 14.0 | 0.6 | NA | NA |
| IAP-a/FL | 16.5 | 0.8 | 0.34 | 0.31 |
| AD6/AD7 | 1.7 | 1.4 | 0.5 | 1.5 |
| AD5/AD7 | 5.2 | 1.0 | 1.1 | 1.9 |
| AD2/AD7 | 316 | 4.8 | 0.5 | 0.2 |
| ADAMTS13 . | Ratio . | |||
|---|---|---|---|---|
| Km . | kcat . | |||
| VWF . | FRETS-VWF73 . | VWF . | FRETS-VWF73 . | |
| C57/FVB | 14.0 | 0.6 | NA | NA |
| IAP-a/FL | 16.5 | 0.8 | 0.34 | 0.31 |
| AD6/AD7 | 1.7 | 1.4 | 0.5 | 1.5 |
| AD5/AD7 | 5.2 | 1.0 | 1.1 | 1.9 |
| AD2/AD7 | 316 | 4.8 | 0.5 | 0.2 |
The Vmax ratios for C57/FVB plasma ADAMTS13 were 0.6 and 0.9, respectively, against substrates VWF and FRETS-VWF73.
NA indicates not applicable.