Engraftment of mast-cell–deficient mice with BMMCs derived from different donors
| . | Mast cells/mm ear cartilage . |
|---|---|
| KitW-sh/W-sh | ND |
| Kit+/+ | 30.6 (± 2.4) |
| TLR7−/− → KitW-sh/W-sh | 28.7 (± 4.2) |
| TNF-α−/− → KitW-sh/W-sh | 25.7 (± 4.1) |
| IL1α/β−/− → KitW-sh/W-sh | 29.7 (± 4.5) |
| Kit+/+ → KitW-sh/W-sh | 26.9 (± 4.5) |
| . | Mast cells/mm ear cartilage . |
|---|---|
| KitW-sh/W-sh | ND |
| Kit+/+ | 30.6 (± 2.4) |
| TLR7−/− → KitW-sh/W-sh | 28.7 (± 4.2) |
| TNF-α−/− → KitW-sh/W-sh | 25.7 (± 4.1) |
| IL1α/β−/− → KitW-sh/W-sh | 29.7 (± 4.5) |
| Kit+/+ → KitW-sh/W-sh | 26.9 (± 4.5) |
Mice were reconstituted as described in “Materials and methods.” After 6 weeks, ear sections were stained with avidin-fluorophor conjugate and mast-cell numbers counted. Shown are the means (± SD) from 4 animals per group.
ND indicates not detectable.