Survival of FLT3/ITD-negative patients according to presence of favorable prognostic factors
| Favorable feature . | No. . | 5-year EFS, ± SEM, % . | Compared with “None” . | 5-year OS, ± SEM, % . | Compared with “None” . | ||
|---|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) . | P . | Hazard ratio (95% CI) . | P . | ||||
| t(8;21) | 27 | 60 ± 10 | 0.40 (0.33-0.80) | .004 | 81 ± 8 | 0.20 (0.25-0.63) | < .001 |
| inv(16) | 26 | 63 ± 10 | 0.36 (0.31-0.77) | .002 | 85 ± 7 | 0.16 (0.23-0.58) | < .001 |
| NPMc+ | 14 | 69 ± 13 | 0.32 (0.26-0.88) | .017 | 77 ± 10 | 0.25 (0.24-0.82) | .009 |
| None | 189 | 28 ± 3 | — | — | 34 ± 4 | — | — |
| Favorable feature . | No. . | 5-year EFS, ± SEM, % . | Compared with “None” . | 5-year OS, ± SEM, % . | Compared with “None” . | ||
|---|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) . | P . | Hazard ratio (95% CI) . | P . | ||||
| t(8;21) | 27 | 60 ± 10 | 0.40 (0.33-0.80) | .004 | 81 ± 8 | 0.20 (0.25-0.63) | < .001 |
| inv(16) | 26 | 63 ± 10 | 0.36 (0.31-0.77) | .002 | 85 ± 7 | 0.16 (0.23-0.58) | < .001 |
| NPMc+ | 14 | 69 ± 13 | 0.32 (0.26-0.88) | .017 | 77 ± 10 | 0.25 (0.24-0.82) | .009 |
| None | 189 | 28 ± 3 | — | — | 34 ± 4 | — | — |