Correlation of biological features of PV and ET patients with respect to the JAK2 617V>F/total JAK2 ratio at the time of diagnosis
| . | PV, n = 100 . | ET, n = 95 . | ||||||
|---|---|---|---|---|---|---|---|---|
| Mean . | SD . | Correlation value . | P . | Mean . | SD . | Correlation value . | P . | |
| JAK2 617V>F/total JAK2 | 0.613 | 0.213 | 1 | 0 | 0.291 | 0.208 | 1 | 0 |
| Age, y | 65 | 14 | −0.0523 | .609 | 59 | 16 | 0.0889 | .402 |
| Hemoglobin, g/L | 189 | 17 | 0.2851 | .004† | 144 | 14 | 0.0706 | .502 |
| Hematocrit, % | 58.1 | 5.7 | 0.2741 | .006† | 43.7 | 1.4 | 0.0892 | .39 |
| Platelet count, × 109/L | 475 | 192 | −0.2953 | .003† | 783 | 242 | 0.4357 | <.001† |
| Leukocytes, × 109/L | 12.3 | 5.8 | 0.1853 | .065 | 9.6 | 4.0 | 0.4453 | <.001† |
| Granulocytes, × 109/L | 9.4 | 4.9 | 0.2465 | .013† | 6.6 | 3.5 | 0.5059 | <.001† |
| Number of colonies (+Epo)* per 2.5 × 105 input cells | 525 | 434 | 0.2374 | .03† | 346 | 315 | 0.0194 7 | .877 |
| Number of EEC (−Epo)* per 2.5 × 105 input cells | 173 | 218 | 0.2800 | .01† | 49 | 91 | 0.3138 | .01† |
| Proportion of EEC* | 0.306 | 0.181 | 0.2605 | .017† | 0.117 | 0.164 | 0.3488 | .004† |
| . | PV, n = 100 . | ET, n = 95 . | ||||||
|---|---|---|---|---|---|---|---|---|
| Mean . | SD . | Correlation value . | P . | Mean . | SD . | Correlation value . | P . | |
| JAK2 617V>F/total JAK2 | 0.613 | 0.213 | 1 | 0 | 0.291 | 0.208 | 1 | 0 |
| Age, y | 65 | 14 | −0.0523 | .609 | 59 | 16 | 0.0889 | .402 |
| Hemoglobin, g/L | 189 | 17 | 0.2851 | .004† | 144 | 14 | 0.0706 | .502 |
| Hematocrit, % | 58.1 | 5.7 | 0.2741 | .006† | 43.7 | 1.4 | 0.0892 | .39 |
| Platelet count, × 109/L | 475 | 192 | −0.2953 | .003† | 783 | 242 | 0.4357 | <.001† |
| Leukocytes, × 109/L | 12.3 | 5.8 | 0.1853 | .065 | 9.6 | 4.0 | 0.4453 | <.001† |
| Granulocytes, × 109/L | 9.4 | 4.9 | 0.2465 | .013† | 6.6 | 3.5 | 0.5059 | <.001† |
| Number of colonies (+Epo)* per 2.5 × 105 input cells | 525 | 434 | 0.2374 | .03† | 346 | 315 | 0.0194 7 | .877 |
| Number of EEC (−Epo)* per 2.5 × 105 input cells | 173 | 218 | 0.2800 | .01† | 49 | 91 | 0.3138 | .01† |
| Proportion of EEC* | 0.306 | 0.181 | 0.2605 | .017† | 0.117 | 0.164 | 0.3488 | .004† |
Spearman correlation test values are indicated. All parameters shown were significantly different when comparing overall ET and PV values by the Student t test (P < .01).
A total of 84 of 100 PV patients and 66 of 95 ET patients had cultures at the time of diagnosis.
Significant P values (< .05) for Spearman correlation test values.