JAK2 617V>F quantification in bone marrow and granulocyte DNA from ET and PV patients
JAK2 617V>F/total JAK2 . | PV samples . | ET samples . | ||
---|---|---|---|---|
Bone marrow, n = 90 . | Granulocytes, n = 93 . | Bone marrow, n = 78 . | Granulocytes, n = 77 . | |
Mean (SD) | 0.598 (0.208) | 0.572 (0.243) | 0.298 (0.193) | 0.270 (0.198) |
Median (range) | 0.50 (0.03–1) | 0.50 (0.1–1) | 0.30 (0.02–0.75) | 0.30 (0.02–0.85) |
Less than 0.20, no. (%) | 1 (1.1) | 4 (4.3) | 19 (24.3) | 25 (32.5) |
0.20 to 0.40, no. (%) | 9 (10.0) | 12 (12.9) | 27 (34.6) | 27 (35.1) |
0.40 to 0.60, no. (%) | 47 (52.2) | 44 (47.3) | 29 (37.2) | 22 (26.6) |
More than 0.60, no. (%) | 33 (36.7) | 33 (35.5) | 3 (3.8) | 3 (3.9) |
JAK2 617V>F/total JAK2 . | PV samples . | ET samples . | ||
---|---|---|---|---|
Bone marrow, n = 90 . | Granulocytes, n = 93 . | Bone marrow, n = 78 . | Granulocytes, n = 77 . | |
Mean (SD) | 0.598 (0.208) | 0.572 (0.243) | 0.298 (0.193) | 0.270 (0.198) |
Median (range) | 0.50 (0.03–1) | 0.50 (0.1–1) | 0.30 (0.02–0.75) | 0.30 (0.02–0.85) |
Less than 0.20, no. (%) | 1 (1.1) | 4 (4.3) | 19 (24.3) | 25 (32.5) |
0.20 to 0.40, no. (%) | 9 (10.0) | 12 (12.9) | 27 (34.6) | 27 (35.1) |
0.40 to 0.60, no. (%) | 47 (52.2) | 44 (47.3) | 29 (37.2) | 22 (26.6) |
More than 0.60, no. (%) | 33 (36.7) | 33 (35.5) | 3 (3.8) | 3 (3.9) |
The numbers (percentages) of patients with various JAK2 617V>F total JAK2 ratios are shown.