Virulence factor distribution: gastric B- and T-cell clonality
| Patient no. . | Sex, age in y . | cagA . | vacA s1 . | vacA s2 . | vacA m1 . | vacA m2 . | ice A1 . | ice A2 . | bab A2 . | IgH . | TCRγ . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients with ITP | |||||||||||
| 39 | M, 83 | + | + | − | + | − | − | + | − | Oligoclonal | ND |
| 41* | M, 78 | − | − | + | − | + | + | − | − | Polyclonal | Polyclonal |
| 42* | F, 30 | − | − | + | − | + | + | − | − | Polyclonal | Polyclonal |
| 47 | M, 47 | + | + | − | + | − | + | + | + | Polyclonal | Monoclonal |
| 48 | F, 27 | + | + | − | − | + | + | − | − | monoclonal | Polyclonal |
| 49 | M, 37 | − | − | + | − | + | + | − | − | Oligoclonal | Monoclonal |
| 50 | M, 37 | + | + | − | − | + | − | + | − | monoclonal | Polyclonal |
| 40 | F, 24 | + | + | − | − | + | - | + | ND | Oligoclonal | Polyclonal |
| 59* | M, 34 | + | + | − | − | + | + | − | + | monoclonal | Polyclonal |
| 58* | F, 45 | + | + | − | − | + | + | − | + | Polyclonal | Monoclonal |
| Control patients without ITP, with gastritis | |||||||||||
| 1 | M, 34 | + | + | − | + | − | + | + | + | Oligoclonal | Monoclonal |
| 2 | M, 89 | − | + | − | − | + | + | − | − | monoclonal | Polyclonal |
| 3 | F, 36 | − | + | − | − | + | − | + | − | Polyclonal | Polyclonal |
| 4 | M, 65 | − | − | + | − | + | + | − | − | Oligoclonal | Monoclonal |
| 5 | M, 60 | − | + | − | − | + | − | + | + | monoclonal | Polyclonal |
| 6 | M, 67 | + | + | − | + | − | − | − | + | Polyclonal | Polyclonal |
| 7 | F, 34 | − | − | + | − | + | + | − | ND | Polyclonal | Polyclonal |
| 8 | M, 74 | − | − | + | − | + | + | − | − | monoclonal | ND |
| 9 | M, 40 | + | + | − | − | + | − | + | + | Oligoclonal | Oligoclonal |
| 10 | F, 53 | + | + | − | − | − | − | + | + | Polyclonal | Polyclonal |
| 11 | M, 78 | − | − | + | − | + | − | + | ND | Polyclonal | Polyclonal |
| 12 | M, 36 | + | + | − | + | − | − | + | + | monoclonal | Polyclonal |
| 13 | F, 40 | − | − | + | − | + | + | − | − | Polyclonal | Polyclonal |
| 14 | F, 51 | − | − | + | − | + | − | − | − | Polyclonal | Oligoclonal |
| 15 | F, 71 | − | − | + | − | + | + | + | + | monoclonal | Monoclonal |
| 16 | F, 73 | − | − | + | − | + | + | − | − | monoclonal | Polyclonal |
| 17 | F, 77 | − | − | + | − | + | + | − | − | Oligoclonal | Polyclonal |
| 18 | F, 51 | − | + | − | + | − | + | − | + | Polyclonal | ND |
| 19 | F, 58 | − | − | + | − | + | + | − | + | Oligoclonal | Polyclonal |
| Patient no. . | Sex, age in y . | cagA . | vacA s1 . | vacA s2 . | vacA m1 . | vacA m2 . | ice A1 . | ice A2 . | bab A2 . | IgH . | TCRγ . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients with ITP | |||||||||||
| 39 | M, 83 | + | + | − | + | − | − | + | − | Oligoclonal | ND |
| 41* | M, 78 | − | − | + | − | + | + | − | − | Polyclonal | Polyclonal |
| 42* | F, 30 | − | − | + | − | + | + | − | − | Polyclonal | Polyclonal |
| 47 | M, 47 | + | + | − | + | − | + | + | + | Polyclonal | Monoclonal |
| 48 | F, 27 | + | + | − | − | + | + | − | − | monoclonal | Polyclonal |
| 49 | M, 37 | − | − | + | − | + | + | − | − | Oligoclonal | Monoclonal |
| 50 | M, 37 | + | + | − | − | + | − | + | − | monoclonal | Polyclonal |
| 40 | F, 24 | + | + | − | − | + | - | + | ND | Oligoclonal | Polyclonal |
| 59* | M, 34 | + | + | − | − | + | + | − | + | monoclonal | Polyclonal |
| 58* | F, 45 | + | + | − | − | + | + | − | + | Polyclonal | Monoclonal |
| Control patients without ITP, with gastritis | |||||||||||
| 1 | M, 34 | + | + | − | + | − | + | + | + | Oligoclonal | Monoclonal |
| 2 | M, 89 | − | + | − | − | + | + | − | − | monoclonal | Polyclonal |
| 3 | F, 36 | − | + | − | − | + | − | + | − | Polyclonal | Polyclonal |
| 4 | M, 65 | − | − | + | − | + | + | − | − | Oligoclonal | Monoclonal |
| 5 | M, 60 | − | + | − | − | + | − | + | + | monoclonal | Polyclonal |
| 6 | M, 67 | + | + | − | + | − | − | − | + | Polyclonal | Polyclonal |
| 7 | F, 34 | − | − | + | − | + | + | − | ND | Polyclonal | Polyclonal |
| 8 | M, 74 | − | − | + | − | + | + | − | − | monoclonal | ND |
| 9 | M, 40 | + | + | − | − | + | − | + | + | Oligoclonal | Oligoclonal |
| 10 | F, 53 | + | + | − | − | − | − | + | + | Polyclonal | Polyclonal |
| 11 | M, 78 | − | − | + | − | + | − | + | ND | Polyclonal | Polyclonal |
| 12 | M, 36 | + | + | − | + | − | − | + | + | monoclonal | Polyclonal |
| 13 | F, 40 | − | − | + | − | + | + | − | − | Polyclonal | Polyclonal |
| 14 | F, 51 | − | − | + | − | + | − | − | − | Polyclonal | Oligoclonal |
| 15 | F, 71 | − | − | + | − | + | + | + | + | monoclonal | Monoclonal |
| 16 | F, 73 | − | − | + | − | + | + | − | − | monoclonal | Polyclonal |
| 17 | F, 77 | − | − | + | − | + | + | − | − | Oligoclonal | Polyclonal |
| 18 | F, 51 | − | + | − | + | − | + | − | + | Polyclonal | ND |
| 19 | F, 58 | − | − | + | − | + | + | − | + | Oligoclonal | Polyclonal |
ND indicates not done.
Nonresponders to eradication treatment.