Detection of relapse markers at diagnosis
| ID . | Relapse rearrangement . | Quantity of relapse clone at diagnosis . |
|---|---|---|
| A1 | VH2-48/D1-26/J4 | ND |
| A2 | VH1-69/D3-10/J6 | 1.0 × 10−5 |
| A3 | VH2-5/D3-3/J4 | 1.0 × 10−4 |
| A4 | VH2-5/D3-22/J4 | ND |
| A5 | VH3-15/D2-15/J4 | ND |
| B1 | VκInt/κdel | NS |
| B6 | VH4-39/D5-5/J4 | 8.7 × 10−3 |
| B7 | VH6-1/D6-13/J2 | 1.2 × 10−1 |
| B8 | VκInt/κdel | ND |
| B14 | Vγ4/Jγ1; Vγ11/Jγ1 | ND; 9.0 × 10−4 |
| B16 | Vκ1/κdel; Vκ7/κdel | ND; 1.01 × 10−5* |
| B19 | VH6-1/D2-8/J6; Vγ11/Jγ2; Vδ2/Dδ3; Dδ2/Dδ3 | 4.5 × 10−4; ND; NS; NS |
| B20 | VH3-23/D6-6/J5 | 9.0 × 10−3 |
| ID . | Relapse rearrangement . | Quantity of relapse clone at diagnosis . |
|---|---|---|
| A1 | VH2-48/D1-26/J4 | ND |
| A2 | VH1-69/D3-10/J6 | 1.0 × 10−5 |
| A3 | VH2-5/D3-3/J4 | 1.0 × 10−4 |
| A4 | VH2-5/D3-22/J4 | ND |
| A5 | VH3-15/D2-15/J4 | ND |
| B1 | VκInt/κdel | NS |
| B6 | VH4-39/D5-5/J4 | 8.7 × 10−3 |
| B7 | VH6-1/D6-13/J2 | 1.2 × 10−1 |
| B8 | VκInt/κdel | ND |
| B14 | Vγ4/Jγ1; Vγ11/Jγ1 | ND; 9.0 × 10−4 |
| B16 | Vκ1/κdel; Vκ7/κdel | ND; 1.01 × 10−5* |
| B19 | VH6-1/D2-8/J6; Vγ11/Jγ2; Vδ2/Dδ3; Dδ2/Dδ3 | 4.5 × 10−4; ND; NS; NS |
| B20 | VH3-23/D6-6/J5 | 9.0 × 10−3 |
Approximate level.
ND indicates not detectable; NS, a specific assay could not be developed.