Titration of the radiation dose from 9 Gy to a cumulative 15 Gy revealed increasingly higher replacement of the T-cell and B-cell populations
| Radiation dose . | TCRβ+ . | B220+ . | CD11b+/IAb+ . |
|---|---|---|---|
| 9 Gy, n=4 | 42.7 ± 3.6 | 95.3 ± 0.8 | 97.9 ± 0.3 |
| 10 Gy, n=8 | 65.7 ± 5.9 | 97.9 ± 0.6 | 98.9 ± 0.3 |
| 2×7.5 Gy, (n=4) | 99.6 ± 0.1 | 99.3 ± 0.2 | 99.3 ± 0.2 |
| Radiation dose . | TCRβ+ . | B220+ . | CD11b+/IAb+ . |
|---|---|---|---|
| 9 Gy, n=4 | 42.7 ± 3.6 | 95.3 ± 0.8 | 97.9 ± 0.3 |
| 10 Gy, n=8 | 65.7 ± 5.9 | 97.9 ± 0.6 | 98.9 ± 0.3 |
| 2×7.5 Gy, (n=4) | 99.6 ± 0.1 | 99.3 ± 0.2 | 99.3 ± 0.2 |
Data are percentages of T cells, B cells, and Kupffer cells replaced by bone marrow–derived cells. KC replacement was already extensive with a 9-Gy radiation dose. Experiments were repeated multiple times with 4 to 8 animals per experimental group.