A comparison of the number of cases with severe complications to severe NAIT in 15 previous prospective studies that have examined the frequency of NAIT and the present study
| Author, reference . | Total no. of pregnant women . | No. of neonates with severe NAIT . | No. of severe complications . | |
|---|---|---|---|---|
| Intracranial hemorrhage . | Intrauterine deaths . | |||
| Mueller-Eckhardt et al21 | 1211 | 0 | 0 | 0 |
| Reznikoff-Etievant et al22 | 860 | 0 | 0 | 0 |
| Blanchette et al23 | 5000 | 1 | 1 | 0 |
| Burrows et al24 * | 15 471 | 10 | 2 | 1 |
| Panzer et al25 * | 923 | 0 | 0 | 0 |
| Doughty et al26 † | 3473 | 2 | 0 | 0 |
| Durand-Zaleski et al27 † | 2066 | 2 | 0 | 0 |
| Dreyfus et al28 *† | 5632 | 4 | 1‡ | 0 |
| de Moerloose et al29 *† | 8388 | 3 | 0 | 1‡ |
| Williamson et al8 † | 24 417 | 10 | 1 | 1‡ |
| Sainio et al31 * | 4489 | 3 | 0 | 0 |
| Uhrynowska et al32 * | 26 275 | 5 | 1 | 0 |
| Davoren et al33 | 4090 | 3 | 0 | 0 |
| Maslanka et al34 † | 8013 | 3 | 1 | 0 |
| Turner et al7 | 26 506 | 5 | 0 | 0 |
| All hitherto published studies | 136 814 | 51 | 7 | 3 |
| The present study | 100 448 | 57§ | 2 | 1§ |
| Author, reference . | Total no. of pregnant women . | No. of neonates with severe NAIT . | No. of severe complications . | |
|---|---|---|---|---|
| Intracranial hemorrhage . | Intrauterine deaths . | |||
| Mueller-Eckhardt et al21 | 1211 | 0 | 0 | 0 |
| Reznikoff-Etievant et al22 | 860 | 0 | 0 | 0 |
| Blanchette et al23 | 5000 | 1 | 1 | 0 |
| Burrows et al24 * | 15 471 | 10 | 2 | 1 |
| Panzer et al25 * | 923 | 0 | 0 | 0 |
| Doughty et al26 † | 3473 | 2 | 0 | 0 |
| Durand-Zaleski et al27 † | 2066 | 2 | 0 | 0 |
| Dreyfus et al28 *† | 5632 | 4 | 1‡ | 0 |
| de Moerloose et al29 *† | 8388 | 3 | 0 | 1‡ |
| Williamson et al8 † | 24 417 | 10 | 1 | 1‡ |
| Sainio et al31 * | 4489 | 3 | 0 | 0 |
| Uhrynowska et al32 * | 26 275 | 5 | 1 | 0 |
| Davoren et al33 | 4090 | 3 | 0 | 0 |
| Maslanka et al34 † | 8013 | 3 | 1 | 0 |
| Turner et al7 | 26 506 | 5 | 0 | 0 |
| All hitherto published studies | 136 814 | 51 | 7 | 3 |
| The present study | 100 448 | 57§ | 2 | 1§ |
Studies examining the platelet counts in a cohort of neonates and for those neonates with low platelet counts the reason for thrombocytopenia was explored.
Studies that employed fetal blood sampling (FBS) as part of their strategy.
Complications associated with FBS. In addition, there was 1 case of acute Caesarean section due to bleeding after FBS but without any sequelae.27
Including 1 stillborn and 1 severely thrombocytopenic live child of born of a woman who mistakenly was not followed up according to the intervention program.