Categorization of lymphoma subtypes according to the Working Formulation and proposed nested classification for 4685 cases from four studies
| Nested classification categories . | Working Formulation categories, % . | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| A: Small lymphocytic; n = 513 . | B-D: Follicular lymphoma; n = 1381 . | E: Diffuse small cleaved cell; n = 244 . | F: Diffuse mixed small and large cell; n = 167 . | G: Diffuse large cell; n = 1165 . | H: Large cell Immunoblastic; n = 447 . | I: Lymphoblastic; n = 83 . | J: Small noncleaved cell; n = 159 . | K: Unknown (n = 526) . | |
| Precursor lymphoblastic leukemia/lymphoma, B- and T-cell | 0 | 0 | 0 | 0 | 2 | 1 | 75 | 2 | 0 |
| B-NHL | 498 | 1341 | 202 | 84 | 1075 | 275 | 27 | 154 | 259 |
| Mature B-NHL | 498 | 1341 | 202 | 84 | 1073 | 274 | 6 | 152 | 259 |
| CLL/SLL/PLL/MCL | 294 | 65 | 103 | 6 | 8 | 0 | 6 | 1 | 40 |
| LPL/Waldenström | 70 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4 |
| DLBCL | 1 | 10 | 4 | 40 | 1027 | 272 | 0 | 5 | 13 |
| BL* | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 144 | 1 |
| MZL | 130 | 38 | 64 | 21 | 21 | 2 | 0 | 2 | 158 |
| FL | 3 | 1228 | 30 | 15 | 14 | 0 | 0 | 0 | 11 |
| T-NHL | 2 | 0 | 19 | 62 | 41 | 159 | 54 | 3 | 31 |
| Mature T-NHL | 2 | 0 | 19 | 62 | 41 | 159 | 0 | 3 | 31 |
| MF/SS | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 10 |
| PTCL | 1 | 0 | 10 | 56 | 27 | 140 | 0 | 3 | 8 |
| Unknown | 13 | 40 | 23 | 21 | 49 | 13 | 2 | 2 | 236 |
| Nested classification categories . | Working Formulation categories, % . | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| A: Small lymphocytic; n = 513 . | B-D: Follicular lymphoma; n = 1381 . | E: Diffuse small cleaved cell; n = 244 . | F: Diffuse mixed small and large cell; n = 167 . | G: Diffuse large cell; n = 1165 . | H: Large cell Immunoblastic; n = 447 . | I: Lymphoblastic; n = 83 . | J: Small noncleaved cell; n = 159 . | K: Unknown (n = 526) . | |
| Precursor lymphoblastic leukemia/lymphoma, B- and T-cell | 0 | 0 | 0 | 0 | 2 | 1 | 75 | 2 | 0 |
| B-NHL | 498 | 1341 | 202 | 84 | 1075 | 275 | 27 | 154 | 259 |
| Mature B-NHL | 498 | 1341 | 202 | 84 | 1073 | 274 | 6 | 152 | 259 |
| CLL/SLL/PLL/MCL | 294 | 65 | 103 | 6 | 8 | 0 | 6 | 1 | 40 |
| LPL/Waldenström | 70 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4 |
| DLBCL | 1 | 10 | 4 | 40 | 1027 | 272 | 0 | 5 | 13 |
| BL* | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 144 | 1 |
| MZL | 130 | 38 | 64 | 21 | 21 | 2 | 0 | 2 | 158 |
| FL | 3 | 1228 | 30 | 15 | 14 | 0 | 0 | 0 | 11 |
| T-NHL | 2 | 0 | 19 | 62 | 41 | 159 | 54 | 3 | 31 |
| Mature T-NHL | 2 | 0 | 19 | 62 | 41 | 159 | 0 | 3 | 31 |
| MF/SS | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 10 |
| PTCL | 1 | 0 | 10 | 56 | 27 | 140 | 0 | 3 | 8 |
| Unknown | 13 | 40 | 23 | 21 | 49 | 13 | 2 | 2 | 236 |
Abbreviations are explained in Table 1.
BL refers to the combined categories of Burkitt lymphoma and high-grade B-cell lymphoma, Burkitt-like.