Table 2

Top 20 genes up-regulated in erythroblasts

HGNC identifierDescriptionFold difference, EB/MK
ERAF Erythroid-associated factor 142.3 
CA1 Carbonic anhydrase I 140.9 
TAC3 Neurokinin B precursor 116.6 
GDF15 Growth/differentiation factor 15 73.45 
HBA2 Hemoglobin, α 2 67.3 
PECI Peroxisomal 3,2-trans-enoyl-CoA isomerase 52.5 
PKLR Pyruvate kinase, isozymes R/L 50.0 
CCR7 C-C chemokine receptor type 7 43.5 
TACSTD1 Tumor-associated calcium signal transducer 1 38.8 
HBE1 Hemoglobin ε chain 38.5 
NP_112177.1 MSTP014 37.7 
SELENBP1 Selenium-binding protein 1 36.0 
MARCH2 Membrane-associated RING finger protein 2 35.1 
KRT17 Keratin, type 1 cytoskeletal 17 32.4 
CTSL Cathepsin L 30.0 
KCNH2 Potassium voltage-gated channel subfamily H member 2 29.0 
ELA2B Elastase 2B precursor 27.0 
FAM83A FAM83A 27.7 
CRYZ Quinone oxidoreductase 25.9 
TNFSF7 Tumor necrosis factor ligand superfamily member 7 25.4 
HGNC identifierDescriptionFold difference, EB/MK
ERAF Erythroid-associated factor 142.3 
CA1 Carbonic anhydrase I 140.9 
TAC3 Neurokinin B precursor 116.6 
GDF15 Growth/differentiation factor 15 73.45 
HBA2 Hemoglobin, α 2 67.3 
PECI Peroxisomal 3,2-trans-enoyl-CoA isomerase 52.5 
PKLR Pyruvate kinase, isozymes R/L 50.0 
CCR7 C-C chemokine receptor type 7 43.5 
TACSTD1 Tumor-associated calcium signal transducer 1 38.8 
HBE1 Hemoglobin ε chain 38.5 
NP_112177.1 MSTP014 37.7 
SELENBP1 Selenium-binding protein 1 36.0 
MARCH2 Membrane-associated RING finger protein 2 35.1 
KRT17 Keratin, type 1 cytoskeletal 17 32.4 
CTSL Cathepsin L 30.0 
KCNH2 Potassium voltage-gated channel subfamily H member 2 29.0 
ELA2B Elastase 2B precursor 27.0 
FAM83A FAM83A 27.7 
CRYZ Quinone oxidoreductase 25.9 
TNFSF7 Tumor necrosis factor ligand superfamily member 7 25.4 

Transcripts are ranked based on the fold difference between EBs and MKs as determined using cDNA microarrays.

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