Table 1

Patient immunologic phenotype

PatientControls
Lymphocyte subpopulation*   
    CD3εhigh 17 (0.4) 1111-5183 
    CD3εlow 2688 (63.7) NA 
    CD20+ 1401 (33.2) 144-671 
    CD16+ 174 (4.1) 152-709 
    CD56+ 223-1040 
Serum Ig level   
    IgG 2310 192-515 
    IgA 213 12-31 
    IgM 248 39-92 
    IgE 27 0-150 
Proliferative stimulus§   
    Medium 1254 693 ± 825 
    PHA 1989 222 330 ± 50 643 
    Con A 3695 208 534 ± 52 592 
    PWM 7224 135 520 ± 35 077 
    Candida 1000 45 431 ± 30 989 
    Anti-CD3ε 131 122 953 ± 44 094 
    Autologous cells 745 3163 ± 2874 
    Allogeneic cells 5520 59 818 ± 38 445 
PatientControls
Lymphocyte subpopulation*   
    CD3εhigh 17 (0.4) 1111-5183 
    CD3εlow 2688 (63.7) NA 
    CD20+ 1401 (33.2) 144-671 
    CD16+ 174 (4.1) 152-709 
    CD56+ 223-1040 
Serum Ig level   
    IgG 2310 192-515 
    IgA 213 12-31 
    IgM 248 39-92 
    IgE 27 0-150 
Proliferative stimulus§   
    Medium 1254 693 ± 825 
    PHA 1989 222 330 ± 50 643 
    Con A 3695 208 534 ± 52 592 
    PWM 7224 135 520 ± 35 077 
    Candida 1000 45 431 ± 30 989 
    Anti-CD3ε 131 122 953 ± 44 094 
    Autologous cells 745 3163 ± 2874 
    Allogeneic cells 5520 59 818 ± 38 445 

NA indicates not applicable; PHA, phytohemagglutinin; Con A, concanavalin A; PWM, pokeweed mitogen.

*

Values are expressed as cells/mm3 or (percentage of lymphocytes). Control values are the 95% confidence intervals for 1550 healthy controls.

Values are expressed as mg/dL (IgG, IgA, IgM) or U/mL (IgE). Normal values are the 95% confidence intervals for 12 6-month-old control subjects.

The patient was receiving IVIG when the IgG level was measured.

§

Values are cpm [3H]thymidine incorporation. Controls values are the mean ± SD of responses in 167 healthy controls.

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