Coagulation factor values in the proposita and family members
Factors . | Patient . | Brother . | Mother . | Father . | Sister . |
|---|---|---|---|---|---|
| II:C, % | 9 | 14 | 119 | 97 | 86 |
| V:C, % | 87 | 47 | 74 | 85 | 97 |
| VII:C, % | 6 | 7 | 100 | 68 | 84 |
| IX:C, % | 7 | — | 92 | 85 | — |
| X:C, % | 5 | 7 | 82 | 109 | 116 |
| II Ag, % | 60 | — | 110 | 80 | 80 |
| IX Ag, % | 73 | 70 | — | — | — |
| PC, % | < 1 | < 1 | 89 | 112 | 88 |
| PS, % | < 1 | < 1 | 44 | 40 | 87 |
| PT, s | 49.5/11.5 | > 60/11.5 | 12.7/11.5 | 13.7/11.5 | 13.7/11.5 |
| PT, % | 10 | < 10 | 80 | 70 | 70 |
| PT, s* | 48/11.5 | — | — | — | — |
| PT, %* | 9 | — | — | — | — |
| APTT, s | 60/30 | 56/30 | 36/30 | 38/30 | 33/30 |
| APTT, s* | 60/30 | — | — | — | — |
| AT, % | 102 | 102 | 86 | 84 | 103 |
Factors . | Patient . | Brother . | Mother . | Father . | Sister . |
|---|---|---|---|---|---|
| II:C, % | 9 | 14 | 119 | 97 | 86 |
| V:C, % | 87 | 47 | 74 | 85 | 97 |
| VII:C, % | 6 | 7 | 100 | 68 | 84 |
| IX:C, % | 7 | — | 92 | 85 | — |
| X:C, % | 5 | 7 | 82 | 109 | 116 |
| II Ag, % | 60 | — | 110 | 80 | 80 |
| IX Ag, % | 73 | 70 | — | — | — |
| PC, % | < 1 | < 1 | 89 | 112 | 88 |
| PS, % | < 1 | < 1 | 44 | 40 | 87 |
| PT, s | 49.5/11.5 | > 60/11.5 | 12.7/11.5 | 13.7/11.5 | 13.7/11.5 |
| PT, % | 10 | < 10 | 80 | 70 | 70 |
| PT, s* | 48/11.5 | — | — | — | — |
| PT, %* | 9 | — | — | — | — |
| APTT, s | 60/30 | 56/30 | 36/30 | 38/30 | 33/30 |
| APTT, s* | 60/30 | — | — | — | — |
| AT, % | 102 | 102 | 86 | 84 | 103 |
Coagulation (C) and antigen (Ag) levels are indicated as the percent of normal values.
PC indicates protein C; PS, protein S; AT, antithrombin activity; and —, not done.
The PT and APTT times were also measured after intramuscular phylloquinone administration (2 weeks at 10 mg/d).